Endo-lysosomal dysfunction in neurodegenerative diseases: Opinion on current progress and future direction in the use of exosomes as biomarkers
M Herman, GW Randall, JL Spiegel… - … of the Royal …, 2024 - royalsocietypublishing.org
Over the past two decades, increased research has highlighted the connection between
endosomal trafficking defects and neurodegeneration. The endo-lysosomal network is an …
endosomal trafficking defects and neurodegeneration. The endo-lysosomal network is an …
The role of long noncoding RNAs in amyotrophic lateral sclerosis
D Rajabi, S Khanmohammadi… - Reviews in the …, 2024 - degruyter.com
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with a poor
prognosis leading to death. The diagnosis and treatment of ALS are inherently challenging …
prognosis leading to death. The diagnosis and treatment of ALS are inherently challenging …
[HTML][HTML] Recent advances in extracellular vesicles in amyotrophic lateral sclerosis and emergent perspectives
GJM Afonso, C Cavaleiro, J Valero, SI Mota, E Ferreiro - Cells, 2023 - mdpi.com
Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …
[HTML][HTML] Morphometric and nanomechanical screening of peripheral blood cells with atomic force microscopy for label-free assessment of Alzheimer's disease …
SG Taneva, S Todinova, T Andreeva - International Journal of Molecular …, 2023 - mdpi.com
Neurodegenerative disorders (NDDs) are complex, multifactorial disorders with significant
social and economic impact in today's society. NDDs are predicted to become the second …
social and economic impact in today's society. NDDs are predicted to become the second …
[HTML][HTML] Protein biomarkers for the diagnosis and prognosis of Amyotrophic Lateral Sclerosis
L Donini, R Tanel, R Zuccarino, M Basso - Neuroscience Research, 2023 - Elsevier
Abstract Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease, still
incurable. The disease is highly heterogenous both genetically and phenotypically …
incurable. The disease is highly heterogenous both genetically and phenotypically …
[HTML][HTML] Efficient management of energy consumption of electric vehicles using machine learning—A systematic and comprehensive survey
M Adnane, A Khoumsi, JPF Trovão - Energies, 2023 - mdpi.com
Electric vehicles are growing in popularity as a form of transportation, but are still underused
for several reasons, such as their relatively low range and the high costs associated with …
for several reasons, such as their relatively low range and the high costs associated with …
[HTML][HTML] Cerebrospinal fluid and blood exosomes as biomarkers for amyotrophic lateral sclerosis; a systematic review
S Darabi, A Ariaei, A Rustamzadeh, D Afshari… - Diagnostic …, 2024 - Springer
Background Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron
disease. Due to the limited knowledge about potential biomarkers that help in early …
disease. Due to the limited knowledge about potential biomarkers that help in early …
[HTML][HTML] Central nervous system-derived extracellular vesicles: the next generation of neural circulating biomarkers?
RC Bravo-Miana, JK Arizaga-Echebarria… - Translational …, 2024 - Springer
The central nervous system (CNS) is integrated by glial and neuronal cells, and both release
extracellular vesicles (EVs) that participate in CNS homeostasis. EVs could be one of the …
extracellular vesicles (EVs) that participate in CNS homeostasis. EVs could be one of the …
Extracellular Vesicles as Next-Generation Diagnostics and Advanced Therapy Medicinal Products
A Stawarska, M Bamburowicz-Klimkowska… - International Journal of …, 2024 - mdpi.com
Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and
therapeutic modalities. This paper describes major GMP-based upstream and downstream …
therapeutic modalities. This paper describes major GMP-based upstream and downstream …
[HTML][HTML] Extracellular vesicles as nanotheranostic platforms for targeted neurological disorder interventions
HK Choi, M Chen, LL Goldston, KB Lee - Nano Convergence, 2024 - Springer
Abstract Central Nervous System (CNS) disorders represent a profound public health
challenge that affects millions of people around the world. Diseases such as Alzheimer's …
challenge that affects millions of people around the world. Diseases such as Alzheimer's …