Over the past two decades, increased research has highlighted the connection between
endosomal trafficking defects and neurodegeneration. The endo-lysosomal network is an …

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with a poor
prognosis leading to death. The diagnosis and treatment of ALS are inherently challenging …

Amyotrophic lateral sclerosis (ALS) is a severe and incurable neurodegenerative disease
characterized by the progressive death of motor neurons, leading to paralysis and death. It is …

Neurodegenerative disorders (NDDs) are complex, multifactorial disorders with significant
social and economic impact in today's society. NDDs are predicted to become the second …

Abstract Amyotrophic Lateral Sclerosis (ALS) is the most common motor neuron disease, still
incurable. The disease is highly heterogenous both genetically and phenotypically …

Electric vehicles are growing in popularity as a form of transportation, but are still underused
for several reasons, such as their relatively low range and the high costs associated with …

Background Amyotrophic lateral sclerosis (ALS) is a progressive and fatal motor neuron
disease. Due to the limited knowledge about potential biomarkers that help in early …

The central nervous system (CNS) is integrated by glial and neuronal cells, and both release
extracellular vesicles (EVs) that participate in CNS homeostasis. EVs could be one of the …

Extracellular vesicles (EVs) hold great promise for clinical application as new diagnostic and
therapeutic modalities. This paper describes major GMP-based upstream and downstream …

Abstract Central Nervous System (CNS) disorders represent a profound public health
challenge that affects millions of people around the world. Diseases such as Alzheimer's …