The role of gut dysbiosis in the pathophysiology of neuropsychiatric disorders

N Anand, VR Gorantla, SB Chidambaram - Cells, 2022 - mdpi.com
Mounting evidence shows that the complex gut microbial ecosystem in the human
gastrointestinal (GI) tract regulates the physiology of the central nervous system (CNS) via …

Gut microbiome: what we do and don't know

GA Cresci, E Bawden - Nutrition in Clinical Practice, 2015 - Wiley Online Library
Within the last decade, research regarding the human gut microbiome has exploded. While
the gastrointestinal tract was once regarded simply as a digestive organ, new technologies …

“More than skin deep”: stress neurobiology and mental health consequences of racial discrimination

M Berger, Z Sarnyai - Stress, 2015 - Taylor & Francis
Ethnic minority groups across the world face a complex set of adverse social and
psychological challenges linked to their minority status, often involving racial discrimination …

The effects of chronic stress on health: new insights into the molecular mechanisms of brain–body communication

A Mariotti - Future science OA, 2015 - Taylor & Francis
GC-dependent negative feedback mechanism that controls the stress response does not
work, GC receptor resistance develops, and the systemic levels of the molecular mediators …

The hippocampus in aging and disease: from plasticity to vulnerability

T Bartsch, P Wulff - Neuroscience, 2015 - Elsevier
The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

Animal models of major depression and their clinical implications

B Czéh, E Fuchs, O Wiborg, M Simon - Progress in neuro …, 2016 - Elsevier
Major depressive disorder is a common, complex, and potentially life-threatening mental
disorder that imposes a severe social and economic burden worldwide. Over the years …

Adult neuroplasticity: more than 40 years of research

E Fuchs, G Flügge - Neural plasticity, 2014 - Wiley Online Library
Within the last four decades, our view of the mature vertebrate brain has changed
significantly. Today it is generally accepted that the adult brain is far from being fixed. A …

Chronic stress and glucocorticoids: from neuronal plasticity to neurodegeneration

S Vyas, AJ Rodrigues, JM Silva, F Tronche… - Neural …, 2016 - Wiley Online Library
Stress and stress hormones, glucocorticoids (GCs), exert widespread actions in central
nervous system, ranging from the regulation of gene transcription, cellular signaling …

[HTML][HTML] Cerebral consequences of environmental noise exposure

O Hahad, MTB Jimenez, M Kuntic, K Frenis… - Environment …, 2022 - Elsevier
The importance of noise exposure as a major environmental determinant of public health is
being increasingly recognized. While in recent years a large body evidence has emerged …

[HTML][HTML] The human hypothalamus in mood disorders: the HPA axis in the center

AM Bao, DF Swaab - IBRO reports, 2019 - Elsevier
There are no specific structural neuropathological hallmarks found in the brain of mood
disorders. Instead, there are molecular, functional and structural alterations reported in many …