The biomechanical properties of extracellular matrices (ECM) and their consequences for
cellular homeostasis have recently emerged as a driver of aging. Here we review the age …

The pulmonary extracellular matrix (ECM) is a macromolecular structure that provides
mechanical support, stability and elastic recoil for different pulmonary cells including the …

Hyaluronic acid (HA), also known as hyaluronan, is an anionic glycosaminoglycan widely
distributed throughout various tissues of the human body. It stands out from other …

To create functional tissue engineering scaffolds, biomaterials should mimic the native
extracellular matrix of the tissue to be regenerated. Simultaneously, the survival and …

Background Rhinovirus infections commonly evoke asthma exacerbations in children and
adults. Recurrent asthma exacerbations are associated with injury-repair responses in the …

The extracellular matrix (ECM) imparts critical mechanical and biochemical information to
cells in the lungs. Proteoglycans are essential constituents of the ECM and play a crucial …

Lipids are major actors and regulators of physiological processes within the lung. Initial
research has described their critical role in tissue homeostasis and in orchestrating cellular …

The extracellular matrix (ECM), composed of interlinked proteins outside of cells, is an
important component of the human body that helps maintain tissue architecture and cellular …

Irreversible alveolar airspace enlargement is the main characteristic of pulmonary
emphysema, which has been extensively studied using animal models. While the alterations …

The extracellular matrix (ECM) supports lung tissue architecture and physiology by providing
mechanical stability and elastic recoil. Over the last several decades, it has become …