Although nontherapeutic xenobiotics represent the vast majority of environmental exposures
during childhood, study of these compounds in children has lagged behind drug studies …

The place of digoxin in the pediatric cardiologist's armamentarium remains uncertain. As an
antiarrhythmic, its use in the Wolff-Parkinson-White syndrome is obsolete, but it remains …

Rational drug treatment for infants and children requires an understanding of the wide
variability in drug handling and response in the early years of life. Such understanding …

Severe illness at any age is accompanied by organ dysfunction, the administration of
numerous drugs and complex changes in drug absorption, disposition and action. The …

Nutrients essential for fetal growth and development require an active transport system to be
moved from the maternal circulation to the fetal circulation against a concentration gradient …

The inotropic and electrophysiologic effects of digoxin were studied in anesthetized
neonatal and adult dogs to test the hypothesis that digoxin had comparable effects in these …

The purpose of this article is to provide the pharmacist with direction in providing
pharmaceutical care to pediatric patients. A major component of the provision of …

The provision of perioperative care for neonates, infants, and children demands
appreciation of developmental changes regarding the pharmacology of anesthetic drugs …

Rational drug therapy requires the application of pharmacologic principles to maximize
efficacy while minimizing adverse reactions. In the setting of the Pediatric Intensive Care …

Dosage requirements are different in the pediatric population due to ongoing development
in pediatric patients from birth to adulthood. The pharmacologic response will depend on …