Silibinin is a major component of Silymarin mixture (Silybum marianum), which has
traditionally been used to treat a wide range of liver diseases. Recently, Silibinin and its …

Induction of lethal autophagy has become a strategy to eliminate glioma cells, but it remains
elusive whether autophagy contributes to cell death via causing mitochondria damage and …

Background Silibinin, the principal flavonoid derived from milk thistle seeds, has been
demonstrated to have strong inhibitory effects against human malignancies. The inhibitory …

Silybin is considered to be the main biologically active component of silymarin. Its oxidized
derivative 2, 3-dehydrosilybin typically occurs in silymarin in small, but non-negligible …

OBJECTIVE: Ovarian cancer is prone to chemoresistance, leading to poor outcomes in
patients. MicroRNA 1301 plays a regulatory role in multiple tumors. However, whether …

Ovarian cancer has long been considered the second-highest cancer threat to women's
reproductive system with high mortality. This is ascribed to the absence of highly efficient …

The prevalence of multidrug-resistant (MDR) strains has caused serious problems in the
treatment of burn infections. MDR Enterobacter cloacae and Enterobacter hormaechei have …

Background: Ovarian cancer (OC) is a commonly diagnosed female cancer around the
world. The Chinese herbal medicine Brucea Javanica has an anti-cancer effect. However …

Research progress on pharmacological effects of silibinin is reviewed. Studies have
confirmed that silibinin has various pharmacological activities, such as anti-tumor, liver …

Osteosarcoma (OS) is a group of malignant tumors with high rates of malignancy and
metastasis. OS most commonly affects adolescents and young individuals. However, owing …