Ferroptosis is an iron-dependent programmed cell death pattern that is characterized by iron
overload, reactive oxygen species (ROS) accumulation and lipid peroxidation. Growing …

A PRoliferation-Inducing Ligand (APRIL), the thirteenth member of the tumor necrosis factor
superfamily, plays a key role in the regulation of activated B cells, the survival of long-lived …

Tumor necrosis factor-α (TNF-α) is a potent pro-inflammatory cytokine, involved in the
pathogenesis and progression of immunoglobulin A nephropathy (IgAN). A bi-allelic …

Background IgA nephropathy (IgAN) is the most prevalent primary glomerulonephritis
worldwide and a leading cause of chronic kidney failure. There are currently no definitive …

IgA nephropathy (IgAN) represents the main cause of renal failure, while the precise
pathogenetic mechanisms have not been fully determined. Herein, we conducted a cross …

Objective: To provide an overview of the guidelines on the management of immunoglobulin
A nephropathy (IgAN) and focal segmental glomerulosclerosis (FSGS), review the evidence …

Ethnopharmacological relevance Immunoglobulin A nephropathy (IgAN) is the most
common primary glomerulonephritis in the world, it is one of the most common causes of …

Abstract Background Immunoglobulin A Nephropathy (IgAN) is a heterogeneous disorder.
Multiple ethnicities conducted studies to assess the effectiveness of the Oxford classification …

Immunoglobulin A nephropathy (IgAN), one type of glomerulonephritis, displays the
accumulation of glycosylated IgA in the mesangium. Studies have demonstrated that both …

Mesangial proliferative glomerulonephritis (MsPGN) and its related rat model Thy-1 nephritis
(Thy-1N) are associated with C5b-9 deposition and are characterized by proliferation of …