Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

Precision medicine is medicine optimized to the genotypic and phenotypic characteristics of
an individual and, when present, his or her disease. It has a host of targets, including genes …

The risk of cancer and associated mortality increases substantially in humans from the age
of 65 years onwards,,,,–. Nonetheless, our understanding of the complex relationship …

Highly efficient and accurate selection of elite genotypes can lead to dramatic shortening of
the breeding cycle in major crops relevant for sustaining present demands for food, feed …

With the genomic revolution in the early 1990s, medical research has been driven to study
the basis of human disease on a genomic level and to devise precise cancer therapies …

Metabolomics refers to the technology for the comprehensive analysis of metabolites and
low-molecular-weight compounds in a biological system, such as cells or tissues …

Metabolomics deals with multiple and complex chemical reactions within living organisms
and how these are influenced by external or internal perturbations. It lies at the heart of …

Dynamic changes in circulating and tissue metabolites and lipids occur in response to
exercise-induced cellular and whole-body energy demands to maintain metabolic …

Abstract 2D NMR is extensively used in many different fields, and its potential for the study of
complex biochemical or chemical mixtures has been widely demonstrated. 2D NMR gives …

Metabolism is at the cornerstone of all cellular functions and mounting evidence of its
deregulation in different diseases emphasizes the importance of a comprehensive …