Diabetes is a chronic metabolic disease that is increasing in prevalence and causes many
complications. Diabetic cardiomyopathy (DCM) is a complication of diabetes that is …

Melatonin interacts in multiple ways with microglia, both directly and, via routes of crosstalk
with astrocytes and neurons, indirectly. These effects of melatonin are of relevance in terms …

The molecular pathology of multi-organ injuries in COVID-19 patients remains unclear,
preventing effective therapeutics development. Here, we report a proteomic analysis of 144 …

Protein phosphorylation is an important post‐transcriptional modification involving an
extremely wide range of intracellular signaling transduction pathways, making it an …

Statins are a class of drugs widely used worldwide to manage hypercholesterolemia and the
prevention of secondary heart attacks. Currently, available statins vary in terms of their …

Vascular remodeling refers to changes in the size, contraction, distribution, and flow rate of
blood vessels and even changes in vascular function. Vascular remodeling can cause …

In the last two decades, the study of the renin–angiotensin–aldosterone system (RAAS) has
revealed a counterregulatory protective axis. This protective arm is characterized by …

Fibrosis and pneumonitis are the most important side effects of lung tissue following cancer
therapy. Radiotherapy and chemotherapy by some drugs, such as bleomycin, can induce …

Cardiovascular disorders are the world's major cause of death nowadays. To treat
cardiovascular diseases especially coronary artery diseases and hypertension, researchers …

The high prevalence of cardiovascular disease in patients with chronic kidney disease
indicates significant interactions between pathogenic pathways operating in the kidney and …