Exogenous GDF11 attenuates non-canonical TGF-β signaling to protect the heart from acute myocardial ischemia–reperfusion injury
HH Su, JM Liao, YH Wang, KM Chen, CW Lin… - Basic Research in …, 2019 - Springer
Abstract Growth differentiation factor 11 (GDF11) is a member of the transforming growth
factor beta 1 (TGF-β1) superfamily that reverses age-related cardiac hypertrophy, improves …
factor beta 1 (TGF-β1) superfamily that reverses age-related cardiac hypertrophy, improves …
Fatty acid-binding protein 3 contributes to ischemic heart injury by regulating cardiac myocyte apoptosis and MAPK pathways
L Zhuang, C Li, Q Chen, Q Jin, L Wu… - American Journal …, 2019 - journals.physiology.org
Fatty acid-binding protein 3 (FABP3), a low-molecular-weight protein, participates in lipid
transportation, storage, signaling transduction, oxidation, and transcription regulation. Here …
transportation, storage, signaling transduction, oxidation, and transcription regulation. Here …
Sphingosine-1-phosphate interactions in the spleen and heart reflect extent of cardiac repair in mice and failing human hearts
Sphingosine-1-phosphate (S1P) is a bioactive mediator in inflammation. Dysregulated S1P
is demonstrated as a cause of heart failure (HF). However, the time-dependent and …
is demonstrated as a cause of heart failure (HF). However, the time-dependent and …
Humoral transfer and intramyocardial signal transduction of protection by remote ischemic perconditioning in pigs, rats, and mice
A Skyschally, P Kleinbongard… - American Journal …, 2018 - journals.physiology.org
Remote ischemic perconditioning (RPER) during ongoing myocardial ischemia reduces
infarct size. The signal transduction of RPER's cardioprotection is still largely unknown …
infarct size. The signal transduction of RPER's cardioprotection is still largely unknown …
Cardioprotection by post-conditioning with exogenous triiodothyronine in isolated perfused rat hearts and isolated adult rat cardiomyocytes
HR Lieder, F Braczko, N Gedik, M Stroetges… - Basic research in …, 2021 - Springer
Ischemic post-conditioning (iPoCo) by coronary re-occlusion/reperfusion during immediate
reperfusion after prolonged myocardial ischemia reduces infarct size. Mechanical …
reperfusion after prolonged myocardial ischemia reduces infarct size. Mechanical …
PPAR alpha activation by clofibrate alleviates ischemia/reperfusion injury in metabolic syndrome rats by decreasing cardiac inflammation and remodeling and by …
M Sánchez-Aguilar, L Ibarra-Lara… - International Journal of …, 2023 - mdpi.com
Metabolic syndrome (MetS) is a cluster of factors that increase the risk of developing
diabetes, stroke, and heart failure. The pathophysiology of injury by ischemia/reperfusion …
diabetes, stroke, and heart failure. The pathophysiology of injury by ischemia/reperfusion …
[HTML][HTML] Molecular imaging of inflammation crosstalk along the cardio-renal axis following acute myocardial infarction
Rationale: Acute myocardial infarction (MI) triggers a systemic inflammatory response
including crosstalk along the heart-kidney axis. We employed radionuclide-based …
including crosstalk along the heart-kidney axis. We employed radionuclide-based …
Remote ischemic preconditioning fails to reduce infarct size in the Zucker fatty rat model of type-2 diabetes: role of defective humoral communication
J Wider, VVR Undyala, P Whittaker, J Woods… - Basic research in …, 2018 - Springer
Remote ischemic preconditioning (RIPC), the phenomenon whereby brief ischemic
episodes in distant tissues or organs render the heart resistant to infarction, has been …
episodes in distant tissues or organs render the heart resistant to infarction, has been …
Reevaluating methods reporting practices to improve reproducibility: an analysis of methodological rigor for the Langendorff whole heart technique
In recent decades, the scientific community has seen an increased interest in rigor and
reproducibility. In 2017, concerns about methodological thoroughness and reporting …
reproducibility. In 2017, concerns about methodological thoroughness and reporting …
Engineering immunomodulatory biomaterials for regenerating the infarcted myocardium
N Bloise, I Rountree, C Polucha… - … in Bioengineering and …, 2020 - frontiersin.org
Coronary artery disease is a severe ischemic condition characterized by the reduction of
blood flow in the arteries of the heart that results in the dysfunction and death of cardiac …
blood flow in the arteries of the heart that results in the dysfunction and death of cardiac …