[HTML][HTML] Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus
NR Jespersen, MV Hjortbak, TR Lassen, NB Støttrup… - Scientific reports, 2020 - nature.com
Ischemia reperfusion (IR) injury may be attenuated through succinate dehydrogenase (SDH)
inhibition by dimethyl malonate (DiMAL). Whether SDH inhibition yields protection in …
inhibition by dimethyl malonate (DiMAL). Whether SDH inhibition yields protection in …
[HTML][HTML] Perturbations in myocardial perfusion and oxygen balance in swine with multiple risk factors: a novel model of ischemia and no obstructive coronary artery …
J van de Wouw, O Sorop, RWA van Drie… - Basic Research in …, 2020 - Springer
Comorbidities of ischemic heart disease, including diabetes mellitus (DM),
hypercholesterolemia (HC) and chronic kidney disease (CKD), are associated with coronary …
hypercholesterolemia (HC) and chronic kidney disease (CKD), are associated with coronary …
Guidelines on antibody use in physiology research
HL Brooks, LE de Castro Brás… - American Journal …, 2024 - journals.physiology.org
Antibodies are one of the most used reagents in scientific laboratories and are critical
components for a multitude of experiments in physiology research. Over the past decade …
components for a multitude of experiments in physiology research. Over the past decade …
Cardiac Troponin I–Interacting Kinase Affects Cardiomyocyte S-Phase Activity but Not Cardiomyocyte Proliferation
SP Reuter, MH Soonpaa, D Field, E Simpson… - Circulation, 2023 - Am Heart Assoc
Background: Identifying genetic variants that affect the level of cell cycle reentry and
establishing the degree of cell cycle progression in those variants could help guide …
establishing the degree of cell cycle progression in those variants could help guide …
[HTML][HTML] Outcomes of hypothalamic oxytocin neuron-driven cardioprotection after acute myocardial infarction
KJ Schunke, J Rodriguez, J Dyavanapalli… - Basic research in …, 2023 - Springer
Altered autonomic balance is a hallmark of numerous cardiovascular diseases, including
myocardial infarction (MI). Although device-based vagal stimulation is cardioprotective …
myocardial infarction (MI). Although device-based vagal stimulation is cardioprotective …
Human biventricular electromechanical simulations on the progression of electrocardiographic and mechanical abnormalities in post-myocardial infarction
Aims Develop, calibrate and evaluate with clinical data a human electromechanical
modelling and simulation framework for multiscale, mechanistic investigations in healthy …
modelling and simulation framework for multiscale, mechanistic investigations in healthy …
Myocardial ischemia: lack of coronary blood flow, myocardial oxygen supply-demand imbalance, or what?
G Heusch - American Journal of Physiology-Heart and …, 2019 - journals.physiology.org
This opinionated article reviews current concepts of myocardial ischemia. Specifically, the
historical background is briefly presented. Then, the prevailing paradigm of myocardial …
historical background is briefly presented. Then, the prevailing paradigm of myocardial …
Diminished reactive hematopoiesis and cardiac inflammation in a mouse model of recurrent myocardial infarction
S Cremer, MJ Schloss, C Vinegoni, BH Foy… - Journal of the American …, 2020 - jacc.org
Background Recurrent myocardial infarction (MI) is common in patients with coronary artery
disease and is associated with high mortality. Long-term reprogramming of myeloid …
disease and is associated with high mortality. Long-term reprogramming of myeloid …
Cardioprotective efficacy of limb remote ischaemic preconditioning in rats: discrepancy between a meta-analysis and a three-centre in vivo study
Aims Remote ischaemic preconditioning (RIPC) is a robust cardioprotective intervention in
preclinical studies. To establish a working and efficacious RIPC protocol in our laboratories …
preclinical studies. To establish a working and efficacious RIPC protocol in our laboratories …
Chronic Porphyromonas gingivalis lipopolysaccharide induces adverse myocardial infarction wound healing through activation of CD8+ T cells
Y Zaidi, A Corker, VY Vasileva… - American Journal …, 2021 - journals.physiology.org
Oral and gum health have long been associated with incidence and outcomes of
cardiovascular disease. Periodontal disease increases myocardial infarction (MI) mortality …
cardiovascular disease. Periodontal disease increases myocardial infarction (MI) mortality …