[HTML][HTML] Microglia in multiple sclerosis: Protectors turn destroyers
VW Yong - Neuron, 2022 - cell.com
Microglia are implicated in all stages of multiple sclerosis (MS). Microglia alterations are
detected by positron emission tomography in people living with MS prior to the formation of …
detected by positron emission tomography in people living with MS prior to the formation of …
Mechanism-based criteria to improve therapeutic outcomes in progressive multiple sclerosis
In contrast to the multiple disease-modifying therapies that are available for relapsing–
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …
remitting multiple sclerosis (MS), the therapeutic options for progressive MS (PMS) are …
Disease‐modifying therapies and coronavirus disease 2019 severity in multiple sclerosis
MP Sormani, N De Rossi, I Schiavetti… - Annals of …, 2021 - Wiley Online Library
Objective This study was undertaken to assess the impact of immunosuppressive and
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in …
immunomodulatory therapies on the severity of coronavirus disease 2019 (COVID‐19) in …
[HTML][HTML] COVID-19 in patients with multiple sclerosis: associations with disease-modifying therapies
AT Reder, D Centonze, ML Naylor, A Nagpal… - CNS drugs, 2021 - Springer
Abstract Background Disease-modifying therapies (DMTs) for multiple sclerosis (MS) target
immunity and have the potential to increase the risk of severe acute respiratory syndrome …
immunity and have the potential to increase the risk of severe acute respiratory syndrome …
[HTML][HTML] Multiple sclerosis therapies differentially affect SARS-CoV-2 vaccine–induced antibody and T cell immunity and function
JJ Sabatino Jr, K Mittl, WM Rowles, K McPolin… - JCI insight, 2022 - ncbi.nlm.nih.gov
BACKGROUND Vaccine-elicited adaptive immunity is a prerequisite for control of SARS-
CoV-2 infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially …
CoV-2 infection. Multiple sclerosis (MS) disease-modifying therapies (DMTs) differentially …
[HTML][HTML] T helper cells: the modulators of inflammation in multiple sclerosis
M Kunkl, S Frascolla, C Amormino, E Volpe, L Tuosto - Cells, 2020 - mdpi.com
Multiple sclerosis (MS) is a chronic neurodegenerative disease characterized by the
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …
progressive loss of axonal myelin in several areas of the central nervous system (CNS) that …
Targeting B cells to modify MS, NMOSD, and MOGAD: part 1
Ocrelizumab, rituximab, ofatumumab, ublituximab, inebilizumab, and evobrutinib are
immunotherapies that target various B cell–related proteins. Most of these treatments have …
immunotherapies that target various B cell–related proteins. Most of these treatments have …
[HTML][HTML] Regulatory cells in multiple sclerosis: From blood to brain
Multiple sclerosis (MS) is a chronic, autoimmune, and neurodegenerative disease of the
central nervous system (CNS) that affects myelin. The etiology of MS is unclear, although a …
central nervous system (CNS) that affects myelin. The etiology of MS is unclear, although a …
[HTML][HTML] Glatiramer acetate immunomodulation: evidence of neuroprotection and cognitive preservation
A Kasindi, DT Fuchs, Y Koronyo, A Rentsendorj… - Cells, 2022 - mdpi.com
Novel, neuroprotective uses of Copaxone (generic name: glatiramer acetate—GA) are being
examined, primarily in neurological conditions involving cognitive decline. GA is a well …
examined, primarily in neurological conditions involving cognitive decline. GA is a well …
[HTML][HTML] Disease-modifying therapies and SARS-CoV-2 vaccination in multiple sclerosis: an expert consensus
Abstract Coronavirus disease (COVID-19) appeared in December 2019 in the Chinese city
of Wuhan and has quickly become a global pandemic. The disease is caused by the severe …
of Wuhan and has quickly become a global pandemic. The disease is caused by the severe …