Ionic liquids and deep eutectic solvents for the stabilization of biopharmaceuticals: a review

NVP Veríssimo, CU Mussagy, HBS Bento… - Biotechnology …, 2024 - Elsevier
Biopharmaceuticals have allowed the control of previously untreatable diseases. However,
their low solubility and stability still hinder their application, transport, and storage. Hence …

Next-generation sequencing applications for the study of fungal pathogens

S Jiang, Y Chen, S Han, L Lv, L Li - Microorganisms, 2022 - mdpi.com
Next-generation sequencing (NGS) has become a widely used technology in biological
research. NGS applications for clinical pathogen detection have become vital technologies …

Analysis of AAV-extracted DNA by charge detection mass spectrometry reveals genome truncations

LF Barnes, BE Draper, J Kurian, YT Chen… - Analytical …, 2023 - ACS Publications
Adeno-associated virus (AAV) is a widely used gene therapy vector. The intact packaged
genome is a critical quality attribute and necessary for an effective therapeutic. In this work …

DNA sequencing: an overview of solid-state and biological nanopore-based methods

MM Mohammadi, O Bavi - Biophysical reviews, 2022 - Springer
The field of sequencing is a topic of significant interest since its emergence and has become
increasingly important over time. Impressive achievements have been obtained in this field …

Practical guide toward discovery of biomolecules with biostimulant activity

J Li, R Lardon, S Mangelinckx… - Journal of Experimental …, 2024 - academic.oup.com
The growing demand for sustainable solutions in agriculture, critical for crop productivity and
food quality in the face of climate change and reduced agrochemical usage, has brought …

Integrated metabolome, full‐length sequencing, and transcriptome analyses unveil the molecular mechanisms of color formation of the canary yellow and red bracts of …

Y Kang, Y Li, T Zhang, P Wang, W Liu… - The Plant …, 2023 - Wiley Online Library
Bougainvillea is a typical tropical flower of great ornamental value due to its colorful bracts.
The molecular mechanism behind color formation is not well‐understood. Therefore, this …

Exposing the small protein load of bacterial life

L Simoens, I Fijalkowski… - FEMS Microbiology …, 2023 - academic.oup.com
The ever-growing repertoire of genomic techniques continues to expand our understanding
of the true diversity and richness of prokaryotic genomes. Riboproteogenomics laid the …

Application progress of high-throughput sequencing in ocular diseases

X He, N Zhang, W Cao, Y Xing, N Yang - Journal of Clinical Medicine, 2022 - mdpi.com
Ocular diseases affect multiple eye parts and can be caused by pathogenic infections,
complications of systemic diseases, genetics, environment, and old age. Understanding the …

Review on the evolution in DNA-based techniques for molecular characterization and authentication of GMOs

Z Liang, L Ding, M Tang, X Wang, X Chen, J Xu… - Microchemical …, 2024 - Elsevier
Genetically modified (GM) foods have not only improved the yield and quality of food but
also raised public concerns about the safety of GM foods. However, with the continuous …

Naringenin modulates the NO‑cGMP‑PKG signaling pathway by binding to AKT to enhance osteogenic differentiation in hPDLSCs

S Li, Z Xiong, Y Lan, Q Zheng… - International …, 2024 - spandidos-publications.com
Naringenin (NAR) is a prominent flavanone that has been recognized for its capacity to
promote the osteogenic differentiation of human periodontal ligament stem cells (hPDLSCs) …