Hemodynamic Regulation of CD34+ Cell Localization and Differentiation in Experimental Aneurysms

E Sho, M Sho, H Nanjo, K Kawamura… - … , and vascular biology, 2004 - Am Heart Assoc
Objectives—Bone marrow-derived vascular progenitor cells (CD34+) are present in human
and animal models of abdominal aortic aneurysm (AAA) disease. These preterminally …

[HTML][HTML] Nanoparticles effectively target rapamycin delivery to sites of experimental aortic aneurysm in rats

T Shirasu, H Koyama, Y Miura, K Hoshina, K Kataoka… - PLoS …, 2016 - journals.plos.org
Several drugs targeting the pathogenesis of aortic aneurysm have shown efficacy in model
systems but not in clinical trials, potentially owing to the lack of targeted drug delivery. Here …

L-Selectin–Mediated Neutrophil Recruitment in Experimental Rodent Aneurysm Formation

KK Hannawa, JL Eliason, DT Woodrum, CG Pearce… - Circulation, 2005 - Am Heart Assoc
Background—This investigation tested the hypothesis that L-selectin is important in
experimental abdominal aortic aneurysm (AAA) formation in rodents. Methods and Results …

Inhibition of miR-155 attenuates abdominal aortic aneurysm in mice by regulating macrophage-mediated inflammation

Z Zhang, K Liang, G Zou, X Chen, S Shi… - Bioscience …, 2018 - portlandpress.com
The aim of the present study was to identify abdominal aortic aneurysms (AAA)-associated
miR-155 contributing to AAA pathology by regulating macrophage-mediated inflammation …

[HTML][HTML] Challenges and opportunities in abdominal aortic aneurysm research

M Wassef, GR Upchurch Jr, H Kuivaniemi… - Journal of vascular …, 2007 - Elsevier
Abdominal Aortic Aneurysms (AAAs) are associated with advanced age, male gender,
cigarette smoking, atherosclerosis, hypertension, and genetic predisposition. Basic research …

B lymphocytes in abdominal aortic aneurysms

L Zhang, Y Wang - Atherosclerosis, 2015 - Elsevier
Abdominal aortic aneurysm (AAA) is a progressive inflammatory disease of the artery walls.
Immune cells, including B lymphocytes, are implicated in the pathogenesis of AAA through …

[HTML][HTML] Compliance of abdominal aortic aneurysms evaluated by tissue Doppler imaging: correlation with aneurysm size

A Long, L Rouet, A Bissery, P Rossignol… - Journal of vascular …, 2005 - Elsevier
OBJECTIVES: Several studies have shown that an increase in abdominal aortic aneurysm
(AAA) growth rate occurs when the diameter reaches 40 to 50 mm. AAA expansion is related …

[HTML][HTML] Age-related increase in wall stress of the human abdominal aorta: an in vivo study

H Åstrand, Å Rydén-Ahlgren, T Sandgren… - Journal of vascular …, 2005 - Elsevier
BACKGROUND: The regulation of wall stress in the abdominal aorta (AA) of humans might
be of specific interest, because the AA is the most common site for aneurysm formation in …

[HTML][HTML] A novel swine model of abdominal aortic aneurysm

JM Cullen, G Lu, AH Shannon, G Su, A Sharma… - Journal of vascular …, 2019 - Elsevier
Objective Few large-animal models exist for the study of aortic aneurysms. β-
Aminopropionitrile (BAPN) is a compound known to cause aortic aneurysms by inhibiting …

Reduced M2 macrophages and adventitia collagen dampen the structural integrity of blood blister–like aneurysms and induce preoperative rerupture

D Wen, R Chen, H Li, J Zheng, W Fu, Z Shi… - Cell …, 2022 - Wiley Online Library
Objective Blood blister–like aneurysms (BBAs) are extremely rare aneurysms. They are
predisposed to preoperative rerupture with a high case‐fatality rate. Here, we attempt to …