Cellular activation pathways and interaction networks in vascularized composite allotransplantation
Vascularized composite allotransplantation (VCA) is an evolving field of reconstructive
surgery that has revolutionized the treatment of patients with devastating injuries, including …
surgery that has revolutionized the treatment of patients with devastating injuries, including …
Composite tissue allotransplantation: opportunities and challenges
J Iske, Y Nian, R Maenosono, M Maurer… - Cellular & molecular …, 2019 - nature.com
Vascularized composite allotransplants (VCAs) have unique properties because of diverse
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …
tissue components transplanted en mass as a single unit. In addition to surgery, this type of …
Recent developments in extracellular matrix remodeling for fat grafting
X Bi, Y Li, Z Dong, J Zhao, W Wu, J Zou… - Frontiers in Cell and …, 2021 - frontiersin.org
Remodeling of the extracellular matrix (ECM), which provides structural and biochemical
support for surrounding cells, is vital for adipose tissue regeneration after autologous fat …
support for surrounding cells, is vital for adipose tissue regeneration after autologous fat …
Methods of ex vivo analysis of tissue status in vascularized composite allografts
Vascularized composite allotransplantation can improve quality of life and restore
functionality. However, the complex tissue composition of vascularized composite allografts …
functionality. However, the complex tissue composition of vascularized composite allografts …
Genetic Modification of Limbs Using Ex Vivo Machine Perfusion
E Valdivia, T Rother, Y Yuzefovych, F Hack… - Human Gene …, 2022 - liebertpub.com
Genetic engineering is a promising tool to repair genetic disorders, improve graft function, or
reduce immune responses toward allografts. Ex vivo organ perfusion systems have the …
reduce immune responses toward allografts. Ex vivo organ perfusion systems have the …
The disturbed function of neutrophils at the early stage of fat grafting impairs long-term fat graft retention
K Liu, J Cai, H Li, J Feng, C Feng… - Plastic and Reconstructive …, 2018 - journals.lww.com
Background: Fat grafting is a popular soft-tissue filler method; however, the mechanism of its
survival and regeneration is still not fully understood. Neutrophils are the frontier …
survival and regeneration is still not fully understood. Neutrophils are the frontier …
Polyethylene glycol‐fusion repair of sciatic allografts in female rats achieves immunotolerance via attenuated innate and adaptive responses
Ablation/segmental loss peripheral nerve injuries (PNIs) exhibit poor functional recovery due
to slow and inaccurate outgrowth of regenerating axons. Viable peripheral nerve allografts …
to slow and inaccurate outgrowth of regenerating axons. Viable peripheral nerve allografts …
Preservation solutions for attenuation of ischemia–reperfusion injury in vascularized composite allotransplantation
S Datta, AM Fitzpatrick, S Haykal - SAGE Open Medicine, 2021 - journals.sagepub.com
Vascularized composite allotransplantation represents the final level of the reconstructive
ladder, offering treatment options for severe tissue loss and functional deficiencies …
ladder, offering treatment options for severe tissue loss and functional deficiencies …
A chronic rejection model and potential biomarkers for vascularized composite allotransplantation
F Puscz, M Dadras, A Dermietzel, F Jacobsen… - PLoS …, 2020 - journals.plos.org
Background Chronic rejection remains the Achilles heel in vascularized composite
allotransplantation. Animal models to specifically study chronic rejection in vascularized …
allotransplantation. Animal models to specifically study chronic rejection in vascularized …
Vascularized composite allotransplantation versus solid organ transplantation: innate-adaptive immune interphase
K Kadono, M Gruszynski, K Azari… - Current opinion in …, 2019 - journals.lww.com
Vascularized composite allotransplantation versus solid orga... : Current Opinion in Organ
Transplantation Vascularized composite allotransplantation versus solid organ …
Transplantation Vascularized composite allotransplantation versus solid organ …