Gut microbiota in colorectal cancer development and therapy

CC Wong, J Yu - Nature Reviews Clinical Oncology, 2023 - nature.com
Colorectal cancer (CRC) is one of the commonest cancers globally. A unique aspect of CRC
is its intimate association with the gut microbiota, which forms an essential part of the tumour …

Exopolysaccharides from probiotic bacteria and their health potential

J Angelin, M Kavitha - International journal of biological macromolecules, 2020 - Elsevier
Exopolysaccharides (EPS) are extracellular macromolecules excreted as tightly bound
capsule or loosely attached slime layer in microorganisms. They play most prominent role …

[HTML][HTML] Paraprobiotics and Postbiotics of Probiotic Lactobacilli, Their Positive Effects on the Host and Action Mechanisms: A Review

T Teame, A Wang, M Xie, Z Zhang, Y Yang… - Frontiers in …, 2020 - frontiersin.org
Lactobacilli comprise an important group of probiotics for both human and animals. The
emerging concern regarding safety problems associated with live microbial cells is …

[HTML][HTML] Targeting gut microbiota and metabolism as the major probiotic mechanism-An evidence-based review

T Ma, X Shen, X Shi, HA Sakandar, K Quan, Y Li… - Trends in Food Science …, 2023 - Elsevier
Background The human gut hosts complex microbial communities, which are linked to
health and disease. The gut microbiota is continuously reshaped by multiple environmental …

[HTML][HTML] Bacterial exopolysaccharides as emerging bioactive macromolecules: from fundamentals to applications

N Kaur, P Dey - Research in microbiology, 2023 - Elsevier
Microbial exopolysaccharides (EPS) are extracellular carbohydrate polymers forming
capsules or slimy coating around the cells. EPS can be secreted by various bacterial genera …

Effect of probiotics and gut microbiota on anti-cancer drugs: Mechanistic perspectives

A Badgeley, H Anwar, K Modi, P Murphy… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Bacteria present in probiotics, particularly the common Lactobacillus and Bifidobacterium
microbes, have been found to induce anti-cancer action by enhancing cancer cell apoptosis …

The anti-cancer effects and mechanisms of lactic acid bacteria exopolysaccharides in vitro: A review

J Wu, Y Zhang, L Ye, C Wang - Carbohydrate polymers, 2021 - Elsevier
Probiotic lactic acid bacteria (LAB) are a particular group of gram-positive bacteria that are
usually involved in natural ferments and widely used in food manufacture industry. Most of …

Structural features of microbial exopolysaccharides in relation to their antioxidant activity

M Andrew, G Jayaraman - Carbohydrate research, 2020 - Elsevier
Oxidative damage caused by free radicals is an inevitable and pervasive phenomenon that
leads to cell damage and the emergence of diseases including ageing, cancer, diabetes …

[HTML][HTML] The relationship between the structural characteristics of lactobacilli-EPS and its ability to induce apoptosis in colon cancer cells in vitro

U Tukenmez, B Aktas, B Aslim, S Yavuz - Scientific reports, 2019 - nature.com
Colon cancer is one of the most common cancer around the world. Exopolysaccharides
(EPSs) produced by lactobacilli as potential prebiotics have been found to have an anti …

Antitumor mechanisms of an exopolysaccharide from Lactobacillus fermentum on HT-29 cells and HT-29 tumor-bearing mice

F Li, X Jiao, J Zhao, X Liao, Y Wei, Q Li - International Journal of Biological …, 2022 - Elsevier
We have obtained an exopolysaccharide (YL-11 EPS) produced by Lactobacillus fermentum
YL-11 isolated from fermented milk and confirmed that it can effectively inhibit colon cancer …