Synthesis of the first 2-hydroxyanthraquinone substituted cyclotriphosphazenes and their cytotoxic properties
Breast cancer, which is common in women, is the second most common cause of cancer-
related deaths after lung cancer. Colon cancer has the highest mortality rate and the fourth …
related deaths after lung cancer. Colon cancer has the highest mortality rate and the fourth …
Anthraquinones
M Fouillaud, Y Caro, M Venkatachalam… - … Compounds in Food, 2018 - taylorfrancis.com
This chapter describes anthraquinones, their structure, and their occurrence in foods such
as plants, fermented products, and insects. Anthraquinones constitute a large group of …
as plants, fermented products, and insects. Anthraquinones constitute a large group of …
Anti-glioma Natural Products Downregulating Tumor Glycolytic Enzymes from Marine Actinomycete Streptomyces sp. ZZ406
M Chen, W Chai, T Song, M Ma, XY Lian, Z Zhang - Scientific reports, 2018 - nature.com
Marine natural products are important resources for discovering novel anticancer drugs. In
this study, an extract prepared from the culture of a sea anemone-derived actinomycete …
this study, an extract prepared from the culture of a sea anemone-derived actinomycete …
Fungal bioactive compounds in pharmaceutical research and development
Background: Exploration of antibiotics from microorganisms became widespread in the
academia and the industry with the serendipitous discovery of Penicillin from Penicillium …
academia and the industry with the serendipitous discovery of Penicillin from Penicillium …
Marine-derived natural products as anticancer agents
N Saini, R Sirohi, N Saini, P Wadhwa… - Medicinal …, 2023 - ingentaconnect.com
Cancer is a deadly human disease on the rise due to changes in lifestyle, nutrition, and
global warming. Cancer is characterized by uncontrolled, disordered, and undesired cell …
global warming. Cancer is characterized by uncontrolled, disordered, and undesired cell …
Epigenetic modulators from “The Big Blue”: A treasure to fight against cancer
Cancer remains a major public health problem in our society. The development of potent
novel anti-cancer drugs selective for tumor cells is therefore still required. Deregulation of …
novel anti-cancer drugs selective for tumor cells is therefore still required. Deregulation of …
New insights into the antimicrobial action and protective therapeutic effect of tirapazamine towards Escherichia coli-infected mice
Z Wu, Y Wang, L Li, S Zhen, H Du, Z Wang… - International Journal of …, 2023 - Elsevier
Objectives Escherichia coli is an important pathogen responsible for numerous cases of
diarrhoea worldwide. The bioreductive agent tirapazamine (TPZ), which was clinically used …
diarrhoea worldwide. The bioreductive agent tirapazamine (TPZ), which was clinically used …
The cyclin-dependent kinase inhibitor SNS-032 induces apoptosis in breast cancer cells via depletion of Mcl-1 and X-linked inhibitor of apoptosis protein and displays …
G Xie, H Tang, S Wu, J Chen… - … journal of oncology, 2014 - spandidos-publications.com
Inhibitors of cyclin-dependent kinases (Cdks) have been reported to have activities in many
types of cancer cells by inhibiting Cdk7 and Cdk9, which control transcription. SNS-032 is a …
types of cancer cells by inhibiting Cdk7 and Cdk9, which control transcription. SNS-032 is a …
Advances in the study of the structures and bioactivities of metabolites isolated from mangrove-derived fungi in the South China Sea
X Wang, ZG Mao, BB Song, CH Chen, WW Xiao, B Hu… - Marine Drugs, 2013 - mdpi.com
Many metabolites with novel structures and biological activities have been isolated from the
mangrove fungi in the South China Sea, such as anthracenediones, xyloketals …
mangrove fungi in the South China Sea, such as anthracenediones, xyloketals …
Discovery of orphan olfactory receptor 6M1 as a new anticancer target in MCF-7 cells by a combination of surface plasmon resonance-based and cell-based systems
YR Choi, J Shim, JH Park, YS Kim, MJ Kim - Sensors, 2021 - mdpi.com
Olfactory receptors (ORs) account for 49% of all G protein-coupled receptors (GPCRs),
which are important targets for drug discovery, and hence ORs may also be potential drug …
which are important targets for drug discovery, and hence ORs may also be potential drug …