Metabolite profiling and genomic properties of an endophytic Bacillus siamensis strain with anti-tumor activity isolated from medicinal plant Curcuma Wenyujin

X Huang, Z Chen, L Wang, J Ran, J Wang… - Plant Cell, Tissue and …, 2024 - Springer
Plant endophytes produce a variety of secondary metabolites that have a wide range of
biological effects. Curcuma wenyujin YH Chen et C. Ling is a medicinal plant of the genus …

[HTML][HTML] A Meroterpenoid from Tibetan medicine induces lung cancer cells apoptosis through ROS-mediated inactivation of the AKT pathway

Y Huang, Y Huang, G Zhu, B Zhang, Y Zhu, B Chen… - Molecules, 2023 - mdpi.com
As a traditional Tibetan medicine in China, Meconopsis grandis Prain has been used to treat
a variety of illnesses by local people for thousands of years. However, the active ingredients …

[HTML][HTML] Anthraquinone G503 induces apoptosis in gastric cancer cells through the mitochondrial pathway

L Huang, T Zhang, S Li, J Duan, F Ye, H Li, Z She… - PloS one, 2014 - journals.plos.org
G503 is an anthraquinone compound isolated from the secondary metabolites of a
mangrove endophytic fungus from the South China Sea. The present study elucidates the …

[HTML][HTML] Investigation into solid and solution properties of quinizarin

D Cheuk, M Svärd, C Seaton, P McArdle… - …, 2015 - pubs.rsc.org
Polymorphism, crystal shape and solubility of 1, 4-dihydroxyanthraquinone (quinizarin) have
been investigated in acetic acid, acetone, acetonitrile, n-butanol and toluene. The solubility …

[HTML][HTML] Evaluation of oyster mushroom (Pleurotus ostreatus)-derived anthraquinone on the induction of apoptosis and suppression of MMP-2 and MMP-9 expression …

B Jayaprakash, AR Suresh… - … Journal of Medical …, 2024 - ncbi.nlm.nih.gov
Introduction: Breast cancer results from tissue degradation caused by environmental and
genetic factors that affect cells in the body. Matrix metalloproteinases, such as MMP-2 and …

A review of natural products and small‐molecule therapeutics acting on central nervous system malignancies: Approaches for drug development, targeting pathways …

A Pasdaran, ID Grice, A Hamedi - Drug Development Research, 2024 - Wiley Online Library
Abstract In 2021, the World Health Organization released the fifth edition of the central
nervous system (CNS) tumor classification. This classification uses histopathology and …

Identification of bostrycin derivatives as potential inhibitors of Mycobacterium tuberculosis protein tyrosine phosphatase (MptpB)

D Chen, H Chen, Z She, Y Lu - Medicinal Chemistry, 2016 - ingentaconnect.com
Background: As a virulence factor secreted into host cells, the Mycobacterium tuberculosis
protein tyrosine phosphatase (MptpB) mediates the intracellular survival of M. tuberculosis …

Research progress of the natural products against prostate cancer

D Fu-Yue, RW JIANG - Chinese Journal of Natural Medicines, 2011 - Elsevier
Prostate cancer is one of the major cancers that threat men's health. At present, a great
number of natural products against prostate cancer have been reported by domestic and …

[HTML][HTML] Developing natural marine products for treating liver diseases

Q Wei, JS Guo - World Journal of Clinical Cases, 2022 - ncbi.nlm.nih.gov
In recent years, marine-derived bioactive compounds have gained increasing attention
because of their higher biodiversity vs land-derived compounds. A number of marine …

Dual function of RGD-modified VEGI-192 for breast cancer treatment

J Wu, Y Jiang, W Yang, Z He, S Meng… - Bioconjugate …, 2012 - ACS Publications
Identification of endogenous angiogenesis inhibitors has led to development of an
increasingly attractive strategy for cancer therapy and other angiogenesis-driven diseases …