Design, synthesis, and biological evaluation of novel 2′-methyl-2′-fluoro-6-methyl-7-alkynyl-7-deazapurine nucleoside analogs as anti-Zika virus agents
G Yao, J Yu, C Lin, Y Zhu, A Duan, M Li, J Yuan… - European Journal of …, 2022 - Elsevier
Zika virus (ZIKV) is a mosquito-borne flavivirus and outbreaks of ZIKV have been reported in
Africa, Americas and other parts of the world lately. The ZIKV epidemic has received …
Africa, Americas and other parts of the world lately. The ZIKV epidemic has received …
Bioactive compounds with antiglioma activity from marine species
R Khotimchenko, I Bryukhovetskiy, M Khotimchenko… - Biomedicines, 2021 - mdpi.com
The search for new chemical compounds with antitumor pharmacological activity is a
necessary process for creating more effective drugs for each specific malignancy type. This …
necessary process for creating more effective drugs for each specific malignancy type. This …
Endophytic fungi from mangrove inhibit lung cancer cell growth and angiogenesis in vitro Corrigendum in/10.3892/or. 2023.8608
X Liu, X Wu, Y Ma, W Zhang, L Hu… - Oncology …, 2017 - spandidos-publications.com
The secondary metabolites of mangrove-derived endophytic fungi contain multiple
substances with novel structures and biological activities. In the present study, three types of …
substances with novel structures and biological activities. In the present study, three types of …
Bioactive norditerpenoids and neolignans from the roots of salvia miltiorrhiza
LZ Li, X Liang, X Sun, XL Qi, J Wang… - Organic & …, 2016 - pubs.rsc.org
Two new norditerpenoids, miltiolactones A and B (1a, 1b); seven new neolignans,
miltiolignanolides A–G (2a, 2b and 3a, 3b and 4a, 4b, and 5) were obtained from the root …
miltiolignanolides A–G (2a, 2b and 3a, 3b and 4a, 4b, and 5) were obtained from the root …
Synthesis and antitumor activities of derivatives of the marine mangrove fungal metabolite deoxybostrycin
H Chen, X Zhu, LL Zhong, B Yang, J Li, JH Wu… - Marine Drugs, 2012 - mdpi.com
Deoxybostrycin (1) is an anthraquinone compound derived from the marine mangrove
fungus Nigrospora sp. No. 1403 and has potential to be a lead for new drugs because of its …
fungus Nigrospora sp. No. 1403 and has potential to be a lead for new drugs because of its …
New polyketides and cytotoxic alkaloids from the mangrove endophytic fungus Talaromyces sp. SAF14
H Li, C Li, K Chen, Z Zhou, Z Chen, B Ding… - Natural Product …, 2024 - Taylor & Francis
Investigation of secondary metabolites from the mangrove endophytic fungus Talaromyces
sp. SAF14 led to the isolation of two new polyketides, methyl (R)-3-(6, 8-dihydroxy-7 …
sp. SAF14 led to the isolation of two new polyketides, methyl (R)-3-(6, 8-dihydroxy-7 …
Fungal metabolites advances in contemporary industrial scenario
JA Takahashi, C Contigli, BA Martins… - Fungal …, 2022 - taylorfrancis.com
Since the discovery of antibiotics, bioactive molecules produced by fungi have played a key
role in the pharmaceutical industry, becoming models for the development of important …
role in the pharmaceutical industry, becoming models for the development of important …
Nutrition and bioprocess development for efficient biosynthesis of an antitumor compound from marine-derived fungus
W Zhou, M Cai, J Zhou, T Jiang, J Zhou… - Journal of Industrial …, 2013 - academic.oup.com
An integrated nutrition and bioprocess strategy was developed for improving the
biosynthesis of an antitumor compound, 1403C, by a marine-derived fungus, Halorosellinia …
biosynthesis of an antitumor compound, 1403C, by a marine-derived fungus, Halorosellinia …
A light–dark shift strategy derived from light-responded metabolic behaviors for polyketides production in marine fungus Halorosellinia sp.
Light, as an important environmental signal, generally brings about a broad regulation in
fungal metabolism. In this work, we aim to explore the light-responded metabolic rules so as …
fungal metabolism. In this work, we aim to explore the light-responded metabolic rules so as …
[HTML][HTML] Streptomyces Levis ABRIINW111 Inhibits SW480 Cells Growth by Apoptosis Induction
BFA Maragheh, P Fatourachi… - Advanced …, 2018 - ncbi.nlm.nih.gov
Purpose: Streptomyces sp., a dominant genus in Actinomycetes, is the source of a wide
variety of secondary metabolites. Microbial metabolites can be utilized as novel anticancer …
variety of secondary metabolites. Microbial metabolites can be utilized as novel anticancer …