Prevalence and risk factors of diabetic retinopathy in migrant Indians in an urbanized society in Asia: the Singapore Indian eye study

Y Zheng, EL Lamoureux, R Lavanya, R Wu, MK Ikram… - Ophthalmology, 2012 - Elsevier
PURPOSE: To describe the prevalence of and risk factors for diabetic retinopathy (DR) in
Indian persons living in a newly urbanized society in Asia. DESIGN: Population-based study …

Synergistic Impact of Visual and Cognitive Impairments on Health-Related Quality of Life in a Multiethnic Asian Population

TA Vu, P Gupta, ATL Gan, EK Fenwick, REK Man… - Gerontology, 2024 - karger.com
Introduction: The concomitant impact of visual impairment (VI) and cognitive impairment (CI)
on health-related quality of life (HRQoL) in older adults is unclear. We aimed to determine …

Retinal nerve fiber layer thickness in a multiethnic normal Asian population: the Singapore epidemiology of eye diseases study

H Ho, YC Tham, ML Chee, Y Shi, NYQ Tan, KH Wong… - Ophthalmology, 2019 - Elsevier
Purpose To describe variations in retinal nerve fiber layer (RNFL) thickness based on
spectral-domain (SD) OCT in a multiethnic Asian population. Design Population-based …

Ancestry, socioeconomic status, and age-related cataract in Asians: the Singapore epidemiology of eye diseases study

J Chua, JY Koh, AG Tan, W Zhao, E Lamoureux… - Ophthalmology, 2015 - Elsevier
Purpose To determine the prevalence of age-related cataract and its ancestral and
socioeconomic risk factors in a multi-ethnic Asian population. Design Population-based …

[HTML][HTML] Elevated serum leptin, adiponectin and leptin to adiponectin ratio is associated with chronic kidney disease in Asian adults

CC Lim, BW Teo, ES Tai, SC Lim, CM Chan, S Sethi… - PLoS one, 2015 - journals.plos.org
Background Adiponectin and leptin, two of the key cytokines secreted by adipocytes, have
been shown to be associated with cardiovascular disease. However, the association of …

Evaluation of generative adversarial networks for high-resolution synthetic image generation of circumpapillary optical coherence tomography images for glaucoma

AJS Kumar, RS Chong, JG Crowston, J Chua… - JAMA …, 2022 - jamanetwork.com
Importance Deep learning (DL) networks require large data sets for training, which can be
challenging to collect clinically. Generative models could be used to generate large …

Analyses of biomarker traits in diverse UK biobank participants identify associations missed by European-centric analysis strategies

Q Sun, M Graff, B Rowland, J Wen, L Huang… - Journal of human …, 2022 - nature.com
Despite the dramatic underrepresentation of non-European populations in human genetics
studies, researchers continue to exclude participants of non-European ancestry, as well as …

A missense variant in FGD6 confers increased risk of polypoidal choroidal vasculopathy

L Huang, H Zhang, CY Cheng, F Wen, POS Tam… - Nature …, 2016 - nature.com
Polypoidal choroidal vasculopathy (PCV), a subtype of'wet'age-related macular
degeneration (AMD), constitutes up to 55% of cases of wet AMD in Asian patients. In …

Singapore Indian Eye Study‐2: methodology and impact of migration on systemic and eye outcomes

C Sabanayagam, W Yip, P Gupta… - Clinical & …, 2017 - Wiley Online Library
Abstract Importance Asian Indians are the fastest growing migration groups in the world.
Studies evaluating the impact of migration on disease outcomes in this population are rare …

[HTML][HTML] ABCC5, a Gene That Influences the Anterior Chamber Depth, Is Associated with Primary Angle Closure Glaucoma

ME Nongpiur, CC Khor, H Jia, BK Cornes… - PLoS …, 2014 - journals.plos.org
Anterior chamber depth (ACD) is a key anatomical risk factor for primary angle closure
glaucoma (PACG). We conducted a genome-wide association study (GWAS) on ACD to …