[HTML][HTML] Gender prediction for a multiethnic population via deep learning across different retinal fundus photograph fields: retrospective cross-sectional study

BK Betzler, HHS Yang, S Thakur, M Yu… - JMIR medical …, 2021 - medinform.jmir.org
Background: Deep learning algorithms have been built for the detection of systemic and eye
diseases based on fundus photographs. The retina possesses features that can be affected …

Prevalence, risk factors and impact of posterior staphyloma diagnosed from wide‐field optical coherence tomography in Singapore adults with high myopia

F Zheng, CW Wong, C Sabanayagam… - Acta …, 2021 - Wiley Online Library
Purpose To investigate the prevalence and risk factors of posterior staphyloma using wide‐
field optical coherence tomography (WF‐OCT) in adults with high myopia in Singapore …

Referral for disease-related visual impairment using retinal photograph-based deep learning: a proof-of-concept, model development study

YC Tham, A Anees, L Zhang, JHL Goh… - The Lancet Digital …, 2021 - thelancet.com
Background In current approaches to vision screening in the community, a simple and
efficient process is needed to identify individuals who should be referred to tertiary eye care …

Association of systemic medication use with intraocular pressure in a multiethnic Asian population: the Singapore Epidemiology of Eye Diseases Study

H Ho, Y Shi, J Chua, YC Tham, SH Lim… - JAMA …, 2017 - jamanetwork.com
Importance There is limited understanding of the associations between systemic medication
use and intraocular pressure (IOP) in the general population. Objective To examine the …

Comparison of common retinal vessel caliber measurement software and a conversion algorithm

WF Yip, YC Tham, W Hsu, ML Lee… - … vision science & …, 2016 - tvst.arvojournals.org
Purpose: To compare three commonly used retinal vessel caliber measurement software
systems, and propose an algorithm for conversion between measurement systems …

Prevalence and predictors of myopic macular degeneration among Asian adults: pooled analysis from the Asian Eye Epidemiology Consortium

YL Wong, X Zhu, YC Tham, JCS Yam… - British Journal of …, 2021 - bjo.bmj.com
Aims To determine the prevalence and predictors of myopic macular degeneration (MMD) in
a consortium of Asian studies. Methods Individual-level data from 19 885 participants from …

Body mass index and retinopathy in Asian populations with diabetes mellitus

D Rooney, WK Lye, G Tan, EL Lamoureux, MK Ikram… - Acta …, 2015 - Springer
Body mass index (BMI) is an established risk factor for diabetes. However, the association
between BMI and diabetic retinopathy (DR) has been inconclusive. We aimed to assess the …

High-density lipoprotein 3 cholesterol and primary open-angle glaucoma: metabolomics and Mendelian randomization analyses

S Nusinovici, H Li, S Thakur, M Baskaran, YC Tham… - Ophthalmology, 2022 - Elsevier
Purpose We hypothesized that the effect of blood lipid–related metabolites on primary open-
angle glaucoma (POAG) would differ according to specific lipoprotein particles and lipid sub …

Customized consensus spectral library building for untargeted quantitative metabolomics analysis with data independent acquisition mass spectrometry and …

G Chen, S Walmsley, GCM Cheung, L Chen… - Analytical …, 2017 - ACS Publications
Data independent acquisition-mass spectrometry (DIA-MS) coupled with liquid
chromatography is a promising approach for rapid, automatic sampling of MS/MS data in …

[HTML][HTML] A global shape index to characterize anterior lamina cribrosa morphology and its determinants in healthy Indian eyes

SG Thakku, YC Tham, M Baskaran… - … & visual science, 2015 - arvojournals.org
Purpose.: Lamina cribrosa (LC) morphology could be implicated in the progression of
glaucoma. To date, no established, quantifiable parameter to assess LC shape in vivo …