Forty-hertz light stimulation does not entrain native gamma oscillations in Alzheimer's disease model mice

M Soula, A Martín-Ávila, Y Zhang, A Dhingra… - Nature …, 2023 - nature.com
There is a demand for noninvasive methods to ameliorate disease. We investigated whether
40-Hz flickering light entrains gamma oscillations and suppresses amyloid-β in the brains of …

Gamma rhythm communication between entorhinal cortex and dentate gyrus neuronal assemblies

A Fernández-Ruiz, A Oliva, M Soula, F Rocha-Almeida… - Science, 2021 - science.org
INTRODUCTION Learning induces a dynamic reorganization of brain circuits but the
neuronal mechanisms underlying this process are not well understood. Interregional gamma …

Hippocampal CA2 sharp-wave ripples reactivate and promote social memory

A Oliva, A Fernández-Ruiz, F Leroy, SA Siegelbaum - Nature, 2020 - nature.com
The consolidation of spatial memory depends on the reactivation ('replay') of hippocampal
place cells that were active during recent behaviour. Such reactivation is observed during …

How our understanding of memory replay evolves

ZS Chen, MA Wilson - Journal of Neurophysiology, 2023 - journals.physiology.org
Memory reactivations and replay, widely reported in the hippocampus and cortex across
species, have been implicated in memory consolidation, planning, and spatial and skill …

Long-duration hippocampal sharp wave ripples improve memory

A Fernández-Ruiz, A Oliva, E Fermino de Oliveira… - Science, 2019 - science.org
Hippocampal sharp wave ripples (SPW-Rs) have been hypothesized as a mechanism for
memory consolidation and action planning. The duration of ripples shows a skewed …

CA2 orchestrates hippocampal network dynamics

A Oliva, A Fernandez‐Ruiz, LA Karaba - Hippocampus, 2023 - Wiley Online Library
The hippocampus is composed of various subregions: CA1, CA2, CA3, and the dentate
gyrus (DG). Despite the abundant hippocampal research literature, until recently, CA2 …

Sleep spindles mediate hippocampal-neocortical coupling during long-duration ripples

HV Ngo, J Fell, B Staresina - elife, 2020 - elifesciences.org
Sleep is pivotal for memory consolidation. According to two-stage accounts, memory traces
are gradually translocated from hippocampus to neocortex during non-rapid-eye-movement …

[PDF][PDF] Hippocampal replays appear after a single experience and incorporate greater detail with more experience

A Berners-Lee, T Feng, D Silva, X Wu, ER Ambrose… - Neuron, 2022 - cell.com
The hippocampus is implicated in memory formation, and neurons in the hippocampus take
part in replay sequences that have been proposed to reflect memory of explored space. By …

Hippocampal gamma and sharp wave/ripples mediate bidirectional interactions with cortical networks during sleep

R Pedrosa, M Nazari, MH Mohajerani… - Proceedings of the …, 2022 - National Acad Sciences
Hippocampus–neocortex interactions during sleep are critical for memory processes:
Hippocampally initiated replay contributes to memory consolidation in the neocortex and …

[PDF][PDF] Subcircuits of deep and superficial CA1 place cells support efficient spatial coding across heterogeneous environments

F Sharif, B Tayebi, G Buzsáki, S Royer… - Neuron, 2021 - cell.com
The hippocampus is thought to guide navigation by forming a cognitive map of space.
Different environments differ in geometry and the availability of cues that can be used for …