[HTML][HTML] Allergen immunotherapy: past, present and future

SR Durham, MH Shamji - Nature Reviews Immunology, 2023 - nature.com
Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

International consensus statement on allergy and rhinology: Allergic rhinitis–2023

SK Wise, C Damask, LT Roland, C Ebert… - International forum of …, 2023 - Wiley Online Library
Background In the 5 years that have passed since the publication of the 2018 International
Consensus Statement on Allergy and Rhinology: Allergic Rhinitis (ICAR‐Allergic Rhinitis …

Efficacy of the omega-3 fatty acids supplementation on inflammatory biomarkers: An umbrella meta-analysis

Z Kavyani, V Musazadeh, S Fathi, AH Faghfouri… - International …, 2022 - Elsevier
Background Existing meta-analyses on omega-3 polyunsaturated fatty acids and their anti-
inflammatory effects have reported uncertain findings. The current umbrella meta-analysis …

One hundred and ten years of allergen immunotherapy: a journey from empiric observation to evidence

O Pfaar, J Bousquet, SR Durham, J Kleine‐Tebbe… - Allergy, 2022 - Wiley Online Library
One hundred and ten years after Noon's first clinical report of the subcutaneous application
of allergen extracts, allergen immunotherapy (AIT) has evolved as the most important pillar …

[HTML][HTML] The immunomodulatory role of withania somnifera (L.) dunal in inflammatory diseases

HH Alanazi, E Elfaki - Frontiers in pharmacology, 2023 - frontiersin.org
Withania somnifera (L.) Dunal (Solanaceae)(also known as Ashwagandha) is a botanical
drug that has been used for centuries to treat many chronic diseases like high blood …

Annexin A2: The diversity of pathological effects in tumorigenesis and immune response

Y Huang, M Jia, X Yang, H Han, G Hou… - … Journal of Cancer, 2022 - Wiley Online Library
Abstract Annexin A2 (ANXA2) is widely used as a marker in a variety of tumors. By
regulating multiple signal pathways, ANXA2 promotes the epithelial‐mesenchymal …

Allergen immunotherapy for long-term tolerance and prevention

M Penagos, SR Durham - Journal of Allergy and Clinical Immunology, 2022 - Elsevier
Allergen immunotherapy is effective for the treatment of allergic rhinitis, allergic asthma, and
Hymenoptera venom allergy. In view of potential side effects, cost, and the necessary patient …

[HTML][HTML] House dust mite allergy: The importance of house dust mite allergens for diagnosis and immunotherapy

HJ Huang, E Sarzsinszky, S Vrtala - Molecular immunology, 2023 - Elsevier
House dust mite (HDM) allergy belongs to the most important allergies and affects
approximately 65–130 million people worldwide. Additionally, untreated HDM allergy may …

[HTML][HTML] Characterization of innate immune responses to house dust mite allergens: pitfalls and limitations

A Jacquet - Frontiers in Allergy, 2021 - frontiersin.org
Whereas house dust mite (HDM) allergy results from a dysregulated Th2-biased adaptive
immune response, activation of innate immune signaling pathways is a critical prerequisite …

Diamino Allose Phosphates: Novel, Potent, and Highly Stable Toll-like Receptor 4 Agonists

JK Khalaf, LS Bess, LM Walsh, JM Ward… - Journal of Medicinal …, 2023 - ACS Publications
Most known synthetic toll-like receptor 4 (TLR4) agonists are carbohydrate-based lipid-A
mimetics containing several fatty acyl chains, including a labile 3-O-acyl chain linked to the …