[HTML][HTML] Industrial biotechnology of Pseudomonas putida: advances and prospects
Pseudomonas putida is a Gram-negative, rod-shaped bacterium that can be encountered in
diverse ecological habitats. This ubiquity is traced to its remarkably versatile metabolism …
diverse ecological habitats. This ubiquity is traced to its remarkably versatile metabolism …
Engineering Native and Synthetic Pathways in Pseudomonas putida for the Production of Tailored Polyhydroxyalkanoates
Growing environmental concern sparks renewed interest in the sustainable production of
(bio) materials that can replace oil‐derived goods. Polyhydroxyalkanoates (PHAs) are …
(bio) materials that can replace oil‐derived goods. Polyhydroxyalkanoates (PHAs) are …
Reconfiguration of metabolic fluxes in Pseudomonas putida as a response to sub-lethal oxidative stress
As a frequent inhabitant of sites polluted with toxic chemicals, the soil bacterium and plant-
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
root colonizer Pseudomonas putida can tolerate high levels of endogenous and exogenous …
[HTML][HTML] A fluoride-responsive genetic circuit enables in vivo biofluorination in engineered Pseudomonas putida
Fluorine is a key element in the synthesis of molecules broadly used in medicine, agriculture
and materials. Addition of fluorine to organic structures represents a unique strategy for …
and materials. Addition of fluorine to organic structures represents a unique strategy for …
[HTML][HTML] Growth-coupled selection of synthetic modules to accelerate cell factory development
Synthetic biology has brought about a conceptual shift in our ability to redesign microbial
metabolic networks. Combining metabolic pathway-modularization with growth-coupled …
metabolic networks. Combining metabolic pathway-modularization with growth-coupled …
A nonconventional archaeal fluorinase identified by in silico mining for enhanced fluorine biocatalysis
Fluorinases, the only enzymes known to catalyze the transfer of fluorine to an organic
molecule, are essential catalysts for the biological synthesis of valuable organofluorines …
molecule, are essential catalysts for the biological synthesis of valuable organofluorines …
[HTML][HTML] Integrated rational and evolutionary engineering of genome-reduced Pseudomonas putida strains promotes synthetic formate assimilation
Formate is a promising, water-soluble C1 feedstock for biotechnology that can be efficiently
produced from CO 2—but formatotrophy has been engineered in only a few industrially …
produced from CO 2—but formatotrophy has been engineered in only a few industrially …
[HTML][HTML] Model-guided dynamic control of essential metabolic nodes boosts acetyl-coenzyme A–dependent bioproduction in rewired Pseudomonas putida
Pseudomonas putida is evolutionarily endowed with features relevant for bioproduction,
especially under harsh operating conditions. The rich metabolic versatility of this species …
especially under harsh operating conditions. The rich metabolic versatility of this species …
[HTML][HTML] Synthetic control of plasmid replication enables target-and self-curing of vectors and expedites genome engineering of Pseudomonas putida
Genome engineering of non-conventional microorganisms calls for the development of
dedicated synthetic biology tools. Pseudomonas putida is a Gram-negative, non-pathogenic …
dedicated synthetic biology tools. Pseudomonas putida is a Gram-negative, non-pathogenic …
Pseudomonas as Versatile Aromatics Cell Factory
Aromatics and their derivatives are valuable chemicals with a plethora of important
applications and thus play an integral role in modern society. Their current production relies …
applications and thus play an integral role in modern society. Their current production relies …