Physiology, signaling, and pharmacology of galanin peptides and receptors: three decades of emerging diversity

R Lang, AL Gundlach, FE Holmes, SA Hobson… - Pharmacological …, 2015 - ASPET
Galanin was first identified 30 years ago as a" classic neuropeptide," with actions primarily
as a modulator of neurotransmission in the brain and peripheral nervous system. Other …

Hypothalamic neuropeptides and the regulation of appetite

JA Parker, SR Bloom - Neuropharmacology, 2012 - Elsevier
Neuropeptides released by hypothalamic neurons play a major role in the regulation of
feeding, acting both within the hypothalamus, and at other appetite regulating centres …

Galanin peptide family regulation of glucose metabolism

P Fang, M Yu, M Shi, P Bo, Z Zhang - Frontiers in Neuroendocrinology, 2020 - Elsevier
Recent preclinical and clinical studies have indicated that the galanin peptide family may
regulate glucose metabolism and alleviate insulin resistance, which diminishes the …

Galanin peptide family as a modulating target for contribution to metabolic syndrome

P Fang, M Yu, M Shi, Z Zhang, Y Sui, L Guo… - General and comparative …, 2012 - Elsevier
Metabolic syndrome (MetS) is defined as abdominal central obesity, atherogenic
dyslipidemia, insulin resistance, glucose intolerance and hypertension. The rapid increasing …

[HTML][HTML] Cytochrome P450 enzymes mediated by DNA methylation is involved in deoxynivalenol-induced hepatoxicity in piglets

A Liu, Y Yang, J Guo, Y Gao, Q Wu, L Zhao, L Sun… - Animal Nutrition, 2022 - Elsevier
Deoxynivalenol (DON) is an inevitable contaminant in animal feed and can lead to liver
damage, then decreasing appetite and causing growth retardation in piglets. Although many …

Galanin-like peptide (GALP) is a hypothalamic regulator of energy homeostasis and reproduction

C Lawrence, GS Fraley - Frontiers in neuroendocrinology, 2011 - Elsevier
Galanin-like peptide (GALP) was discovered in 1999 in the porcine hypothalamus and was
found to be a 60 amino acid neuropeptide. GALP shares sequence homology to galanin (1 …

The regulative effect of galanin family members on link of energy metabolism and reproduction

P Fang, B He, M Shi, G Kong, X Dong, Y Zhu, P Bo… - Peptides, 2015 - Elsevier
It is essential for the species survival that an efficient coordination between energy storage
and reproduction through endocrine regulation. The neuropeptide galanin, one of the …

Effects of alarin on food intake, body weight and luteinizing hormone secretion in male mice

GS Fraley, E Leathley, N Lundy, E Chheng, I King… - Neuropeptides, 2012 - Elsevier
Alarin is a member of the galanin family of neuropeptides that includes galanin and galanin-
like peptide (GALP). Alarin is an alternate transcript of the GALP gene and is expressed in …

Circulating galanin and galanin like peptide concentrations are correlated with increased triglyceride concentration in obese patients

P Fang, M Yu, X Gu, M Shi, Y Zhu, Z Zhang, P Bo - Clinica Chimica Acta, 2016 - Elsevier
Background: Obesity is strongly linked to metabolic complications, including type 2 diabetes
mellitus and hyperlipidemia. Experimental evidences indicate that galanin (GAL) and …

Galanin-like peptide: a key player in the homeostatic regulation of feeding and energy metabolism?

S Shioda, H Kageyama, F Takenoya… - International journal of …, 2011 - nature.com
The hypothalamus has a critical role in the regulation of feeding behavior, energy
metabolism and reproduction. Galanin-like peptide (GALP), a novel 60 amino-acid peptide …