Resistance to immune checkpoint inhibitors in non-small cell lung cancer: biomarkers and therapeutic strategies

RJ Walsh, RA Soo - Therapeutic advances in medical …, 2020 - journals.sagepub.com
The treatment landscape for patients with advanced non-small cell lung cancer has evolved
greatly with the advent of immune checkpoint inhibitors. However, many patients do not …

[HTML][HTML] Effectiveness and safety of immunotherapy in NSCLC patients with ECOG PS score≥ 2–systematic review and meta-analysis

B Tomasik, M Bieńkowski, M Braun, S Popat… - Lung Cancer, 2021 - Elsevier
Abstract Background Immune checkpoint inhibitors (ICIs) are standard of care in advanced
non-small cell lung cancer (NSCLC), however their status in patients with poor performance …

[HTML][HTML] Nivolumab in previously treated advanced gastric cancer (ATTRACTION-2): 3-year update and outcome of treatment beyond progression with nivolumab

N Boku, T Satoh, MH Ryu, Y Chao, K Kato, HC Chung… - Gastric cancer, 2021 - Springer
Background ATTRACTION-2 demonstrated that nivolumab improved overall survival (OS) vs
placebo in patients with advanced gastric cancer treated with≥ 2 chemotherapy regimens …

[HTML][HTML] Combing stereotactic body radiotherapy with checkpoint inhibitors after oligoprogression in advanced non-small cell lung cancer

Z Wang, L Wei, J Li, H Zhou, S Li, D Chen… - Translational Lung …, 2021 - ncbi.nlm.nih.gov
Background Immunotherapy has brought substantial benefit for patients with advanced non-
small cell lung cancer (NSCLC); however, resistance may occur, of which oligoprogression …

[HTML][HTML] Real-life results from the overall population and key subgroups within the Italian cohort of nivolumab expanded access program in non-squamous non–small …

F Grossi, C Genova, L Crinò, A Delmonte… - European Journal of …, 2019 - Elsevier
Background Nivolumab was the first immune checkpoint inhibitor approved for previously
treated advanced non–small cell lung cancer (NSCLC). Before its introduction in the market …

Pseudoprogression in lung cancer patients treated with immunotherapy

MY Chen, YC Zeng - Critical reviews in oncology/hematology, 2022 - Elsevier
Lung cancer has attracted much attention because of its high morbidity and mortality
worldwide. The advent of immunotherapy approaches, especially the application of immune …

Pseudoprogression and hyperprogression in lung cancer: a comprehensive review of literature

L Zhou, M Zhang, R Li, J Xue, Y Lu - Journal of Cancer Research and …, 2020 - Springer
Purpose Immune checkpoint inhibitors are associated with clinical benefit in lung cancer.
However, response patterns to immunotherapy, including pseudoprogression and …

[HTML][HTML] Immunotherapy beyond progression in patients with advanced non-small cell lung cancer

X Ge, Z Zhang, S Zhang, F Yuan, F Zhang… - … lung cancer research, 2020 - ncbi.nlm.nih.gov
Background Immune checkpoint inhibitors (ICIs) represent a great breakthrough in the
treatment of advanced non-small cell lung cancer (aNSCLC). However, whether …

[HTML][HTML] Immune checkpoint inhibitor rechallenge in advanced or metastatic non-small cell lung cancer: a retrospective cohort study

Z Xu, X Hao, K Yang, Q Wang, J Wang, L Lin… - Journal of Cancer …, 2022 - Springer
Purpose After progression to immunotherapy, the standard of care for non-small cell lung
cancer (NSCLC) was limited. Administration of the same or different immune checkpoint …

[HTML][HTML] Outcomes from salvage chemotherapy or pembrolizumab beyond progression with or without local ablative therapies for advanced non-small cell lung …

G Metro, A Addeo, D Signorelli, A Gili… - Journal of thoracic …, 2019 - ncbi.nlm.nih.gov
Background In this real-world multicenter study we addressed the activity of post-
progression anticancer treatments after first-line pembrolizumab in advanced non-small cell …