Acute and chronic kidney injuries result from structural dysfunction and metabolic disorders
of the kidney in various etiologies, which significantly affect human survival and social …

More than 800 million people suffer from kidney disease. Genetic studies and follow-up
animal models and cell biological experiments indicate the key role of proximal tubule …

Kidneys are central in the regulation of multiple physiological functions, such as removal of
metabolic wastes and toxins, maintenance of electrolyte and fluid balance, and control of pH …

Background Observational studies suggest that adequate dietary potassium intake (90–120
mmol/day) may be renoprotective, but the effects of increasing dietary potassium and the risk …

The kidneys have a central role in the control of acid–base homeostasis owing to
bicarbonate reabsorption and production of ammonia and ammonium in the proximal tubule …

The topic of uremic toxicity has received broad attention from the nephrological community
over the past few decades. An aspect that is much less often considered is the possibility …

Acute kidney injury (AKI) is closely associated with the overproduction of reactive oxygen
species (ROS), which can cause multiple organ dysfunctions without timely treatment …

Acute kidney injury (AKI), one of the most prevalent clinical diseases with a high incidence
rate worldwide, is characterized by a rapid deterioration of renal function and further triggers …

Background: In 2004, the term acute kidney injury (AKI) was introduced with the intention of
broadening our understanding of rapid declines in renal function and to replace the …

Systemic acid–base status is primarily determined by the interplay of net acid production
(NEAP) arising from metabolism of ingested food stuffs, buffering of NEAP in tissues …