[HTML][HTML] The effects of amino acid substitution of spike protein and genomic recombination on the evolution of SARS-CoV-2

L Fang, J Xu, Y Zhao, J Fan, J Shen, W Liu… - Frontiers in …, 2023 - frontiersin.org
Over three years' pandemic of 2019 novel coronavirus disease (COVID-19), multiple
variants and novel subvariants have emerged successively, outcompeted earlier variants …

Targeting SARS-CoV-2 entry processes: The promising potential and future of host-targeted small-molecule inhibitors

A Wu, K Shi, J Wang, R Zhang, Y Wang - European Journal of Medicinal …, 2023 - Elsevier
The COVID-19 pandemic, caused by SARS-CoV-2, has had a huge impact on global health.
To respond to rapidly mutating viruses and to prepare for the next pandemic, there is an …

Synthesis, molecular docking, and binding Gibbs free energy calculation of β-nitrostyrene derivatives: Potential inhibitors of SARS-CoV-2 3CL protease

Z Jia, X Lan, K Lu, X Meng, W Jing, S Jia, K Zhao… - Journal of Molecular …, 2023 - Elsevier
The outbreak of novel coronavirus disease 2019 (COVID-19), caused by the novel
coronavirus (SARS-CoV-2), has had a significant impact on human health and the economic …

A Patent Review on SARS Coronavirus Papain‐Like Protease (PLpro) Inhibitors

CS Brian Chia, S Pheng Lim - ChemMedChem, 2023 - Wiley Online Library
The severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) pandemic is an
unprecedented global health emergency causing more than 6.6 million fatalities by 31 …

[HTML][HTML] In vitro testing of host-targeting small molecule antiviral matriptase/TMPRSS2 inhibitors in 2D and 3D cell-based assays

N van Eijk, LC Schmacke, T Steinmetzer… - Biomedicine & …, 2023 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19) pandemic strongly stimulated the
development of small molecule antivirals selectively targeting type II transmembrane serine …

Host factors of SARS-CoV-2 in infection, pathogenesis, and long-term effects

Y Zhang, S Chen, Y Tian, X Fu - Frontiers in Cellular and Infection …, 2024 - frontiersin.org
SARS-CoV-2 is the causative virus of the devastating COVID-19 pandemic that results in an
unparalleled global health and economic crisis. Despite unprecedented scientific efforts and …

[HTML][HTML] Importance, applications and features of assays measuring SARS-CoV-2 neutralizing antibodies

P Gattinger, A Ohradanova-Repic… - International Journal of …, 2023 - mdpi.com
More than three years ago, the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-
CoV-2) caused the unforeseen COVID-19 pandemic with millions of deaths. In the …

[HTML][HTML] Analysis the molecular similarity of least common amino acid sites in ACE2 receptor to predict the potential susceptible species for SARS-CoV-2

YZ Hu, AK Villalan, X Fan, S Zhang, FR Joka, XD Wu… - Plos one, 2024 - journals.plos.org
SARS-CoV-2 infections in animals have been reported globally. However, the
understanding of the complete spectrum of animals susceptible to SARS-CoV-2 remains …

[HTML][HTML] An Update on SARS-CoV-2 Clinical Trial Results—What We Can Learn for the Next Pandemic

BY Arman, J Brun, ML Hill, N Zitzmann… - International Journal of …, 2023 - mdpi.com
The coronavirus disease 2019 (COVID-19) pandemic has claimed over 7 million lives
worldwide, providing a stark reminder of the importance of pandemic preparedness. Due to …

[HTML][HTML] Development of SARS-CoV-2 entry antivirals

M Dong, JMG Achi, R Du, L Rong, Q Cui - Cell Insight, 2024 - Elsevier
The global outbreak of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
threatened human health and public safety. The development of anti-SARS-CoV-2 therapies …