Inflammation-associated diseases encompass a range of infectious diseases and non-
infectious inflammatory diseases, which continuously pose one of the most serious threats to …

With the changing disease spectrum, atherosclerosis has become increasingly prevalent
worldwide and the associated diseases have emerged as the leading cause of death. Due …

Atherosclerosis, a highly prevalent cardiovascular disease, has significantly contributed to
morbidity and mortality worldwide. Despite the availability of various treatment options in …

Directly activating CD8+ T cells within the tumor through antigen-presenting cells (APCs)
hold promise for tumor elimination. However, M2-like tumor-associated macrophages …

Severe acute pancreatitis (AP) is a life-threatening pancreatic inflammatory disease with a
high mortality rate (∼ 40%). Existing pharmaceutical therapies in development or in clinical …

Rationale: Intracerebral hemorrhage (ICH) is a devastating cerebrovascular disease
resulting from blood extravasating into the brain parenchyma. Escalation of …

Sustained and intense inflammation is the pathological basis for intervertebral disc
degeneration (IVDD). Effective antagonism or reduction of local inflammatory factors may …

Osteoporosis, characterized by a reduction in bone mineral density, represents a prevalent
skeletal disorder with substantial global health implications. Conventional therapeutic …

Neutrophils play an essential role as 'first responders' in the immune response,
necessitating many immune-modulating capabilities. Chronic, unresolved inflammation is …

Atherosclerosis is the main cause of a series of fatal cardiovascular diseases, characterized
by pathological accumulation of apoptotic cells and lipids. Pro-phagocytic antibody-based or …