Evaluation of the PIGRET assay in rats by single oral dosing with azidothymidine
H Sanada, T Ohsumi, N Koyama, T Miyashita… - … /Genetic Toxicology and …, 2016 - Elsevier
In vivo phosphatidylinositol glycan, class A (Pig-a) gene mutation assay using peripheral
blood is known to be a novel and useful tool to evaluate the mutagenicity of compounds …
blood is known to be a novel and useful tool to evaluate the mutagenicity of compounds …
Development of a novel 32P-postlabeling method for the analysis of 3′-azido-3′-deoxythymidine
JL Fang, FA Beland - Cancer letters, 2000 - Elsevier
3′-Azido-3′-deoxythymidine (AZT) was the first anti-retroviral nucleoside analog to be
used in the treatment and prevention of acquired immunodeficiency syndrome (AIDS). A …
used in the treatment and prevention of acquired immunodeficiency syndrome (AIDS). A …
Absence of structural or functional alterations in male and female reproductive organs of F1 and F2 generations derived from female mice exposed to 3′-azido-3 …
BA Diwan, OA Olivero, MC Poirier - Toxicology letters, 2000 - Elsevier
To investigate the effects of in utero exposure to 3′-azido-3′-deoxythymidine (AZT) on
male and female reproductive system development, pregnant CD-1 mice were given daily …
male and female reproductive system development, pregnant CD-1 mice were given daily …
Lamivudinin insan periferal lenfositlerinde in vitro genotoksit etkileri
S Bayram - acikbilim.yok.gov.tr
Bu çal man n amac, hepatit B virüsü ile enfekte bireylerin tedavisinde kullan lanlamivudin'in
genotoksik etkisi olup olmad n insan periferal lenfositlerinde in vitro kardekromatid de i imi …
genotoksik etkisi olup olmad n insan periferal lenfositlerinde in vitro kardekromatid de i imi …
[PDF][PDF] Association between Antiretroviral Therapy and Cancers among Children Living with HIV in Sub-Saharan Africa. Cancers 2021, 13, 1379
H Haq, P Elyanu, S Bulsara, JM Bacha… - 2021 - texaschildrensglobalhealth.org
Approximately 91% of the world's children living with HIV (CLWH) are in sub-Saharan Africa
(SSA). Living with HIV confers a risk of developing HIV-associated cancers. To determine …
(SSA). Living with HIV confers a risk of developing HIV-associated cancers. To determine …
An unusual phenotypic and genotypic expression in F2 generation following one stage zidovudine exposure during pregnancy and lactation-an experiment in mice
C Rajlakshmi, JK Roy, AK Rai… - The Journal of …, 2012 - jstage.jst.go.jp
Zidovudine (3'-Azido-2', 3'-dideoxythymidine, AZT, ZDV) is routinely used as one of the
component of antiretroviral therapy to prevent transmission of the HIV infection from mother …
component of antiretroviral therapy to prevent transmission of the HIV infection from mother …
[PDF][PDF] Tenofovir disoproksil fumaratın insan lenfositlerinde genotoksik aktivitesinin incelenmesi
K Kurt, L Dönbak, A Kayraldız - Cukurova Medical Journal, 2016 - researchgate.net
Öz Purpose: Antiretroviral drugs used in the treatment of HIV (Human Immünodeficiency
Virus) iınfection, treat by preventing the proliferation of HIV in human body. People with HIV …
Virus) iınfection, treat by preventing the proliferation of HIV in human body. People with HIV …
Evaluation of genotoxic activity of tenofovir disoproxil fumarate in human peripheral lymphocytes
K Kurt, L Dönbak, A Kayraldız - Cukurova Medical Journal, 2016 - dergipark.org.tr
Öz Purpose: Antiretroviral drugs used in the treatment of HIV (Human Immünodeficiency
Virus) iınfection, treat by preventing the proliferation of HIV in human body. People with HIV …
Virus) iınfection, treat by preventing the proliferation of HIV in human body. People with HIV …
[PDF][PDF] Foetal Loss and Enhanced Fertility Observed in Mice Treated with Zidovudine
Background: Health concerns for HIV-infected persons on antiretroviral therapy (ART) have
moved from morbidity to the challenges of long-term ART. We investigated the effect of …
moved from morbidity to the challenges of long-term ART. We investigated the effect of …
[图书][B] Mechanistic investigations of DNA reactive carcinogens at low dose, through analysis of DNA adducts, mutations and DNA repair
AD Thomas - 2012 - search.proquest.com
Genetic toxicology assesses the genotoxic potential of chemicals in consumer products,
pharmaceuticals and from agricultural and industrial processes. Such assessment is integral …
pharmaceuticals and from agricultural and industrial processes. Such assessment is integral …