Placental malaria (PM) due to Plasmodium falciparum is a major cause of maternal, fetal
and infant mortality, but the mechanisms of pathogenesis and protective immunity are …

Background Malaria in pregnancy has major impacts on mother and child health. To
complement existing interventions, such as intermittent preventive treatment and use of …

Introduction: Malaria during pregnancy is a massive health problem in endemic areas.
Placental malaria infections caused by Plasmodium falciparum are responsible for up to one …

Placental accumulation of Plasmodium falciparum infected erythrocytes results in maternal
anemia, low birth weight, and pregnancy loss. The parasite protein VAR2CSA facilitates the …

The subcellular localization and function of variant subtelomeric multigene families in
Plasmodium vivax remain vastly unknown. Among them, the vir superfamily is putatively …

Var2CSA, a key molecule linked with pregnancy-associated malaria (PAM), causes
sequestration of Plasmodium falciparum infected erythrocytes (PEs) in the placenta by …

Infections with the human malaria parasite Plasmodium falciparum during pregnancy can
lead to severe complications for both mother and child, resulting from the cytoadhesion of …

Background The pathogenesis of malaria in pregnancy (MiP) involves accumulation of P.
falciparum-infected red blood cells (pRBCs) in the placenta, contributing to poor pregnancy …

Background. Placental malaria is caused by Plasmodium falciparum–infected erythrocytes
(IEs) that surface-express VAR2CSA and bind chondroitin sulfate A. The inflammatory …

Background Placental malaria occurs when Plasmodium falciparum infected erythrocytes
sequester in the placenta. Placental parasite isolates bind to chondroitin sulphate A (CSA) …