SARS coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, emerged in China in
December 2019. Vaccines developed were very effective initially, however, the virus has …

Organoid cultures offer a valuable platform for studying organ-level biology, allowing for a
closer mimicry of human physiology compared to traditional two-dimensional cell culture …

The high transmissibility of SARS-CoV-2 Omicron subvariants was generally ascribed to
immune escape. It remained unclear whether the emerging variants have gradually …

The human upper respiratory tract, specifically the nasopharyngeal epithelium, is the entry
portal and primary infection site of respiratory viruses. Productive infection of SARS-CoV-2 in …

Since the emergence of the Omicron variants at the end of 2021, they quickly became the
dominant variants globally. The Omicron variants may be more easily transmitted compared …

Viral infection in respiratory tract usually leads to cell death, impairing respiratory function to
cause severe disease. However, the diversity of clinical manifestations of SARS-CoV-2 …

The prevalency of lung disease has increased worldwide, especially in the aging
population. It is essential to develop novel disease models, that are superior to traditional …

The spread of many infectious diseases relies on aerosol transmission to the respiratory
tract. Here we design an intranasal mask comprising a positively-charged thermosensitive …

Abstract Coronavirus disease 2019 (COVID‐19), a global pandemic caused by the severe
acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), has posed a catastrophic threat …

Background Early studies indicated that vitamin D (VD) exerted pleiotropic extra-skeletal
effects in the airway, but the definite linkage between VD deficiency and airway host …