Advances in the bacterial organelles for CO2 fixation

LN Liu - Trends in Microbiology, 2022 - cell.com
Carboxysomes are a family of bacterial microcompartments (BMCs), present in all
cyanobacteria and some proteobacteria, which encapsulate the primary CO 2-fixing …

Role of carboxysomes in cyanobacterial CO2 assimilation: CO2 concentrating mechanisms and metabolon implications

CA Huffine, R Zhao, YJ Tang… - Environmental …, 2023 - Wiley Online Library
Many carbon‐fixing organisms have evolved CO2 concentrating mechanisms (CCMs) to
enhance the delivery of CO2 to RuBisCO, while minimizing reactions with the competitive …

[HTML][HTML] Intrinsically disordered CsoS2 acts as a general molecular thread for α-carboxysome shell assembly

T Ni, Q Jiang, PC Ng, J Shen, H Dou, Y Zhu… - Nature …, 2023 - nature.com
Carboxysomes are a paradigm of self-assembling proteinaceous organelles found in nature,
offering compartmentalisation of enzymes and pathways to enhance carbon fixation. In α …

[HTML][HTML] A catalog of the diversity and ubiquity of bacterial microcompartments

M Sutter, MR Melnicki, F Schulz, T Woyke… - Nature …, 2021 - nature.com
Bacterial microcompartments (BMCs) are organelles that segregate segments of metabolic
pathways which are incompatible with surrounding metabolism. BMCs consist of a …

Structure and assembly of the α-carboxysome in the marine cyanobacterium Prochlorococcus

RQ Zhou, YL Jiang, H Li, P Hou, WW Kong, JX Deng… - Nature Plants, 2024 - nature.com
Carboxysomes are bacterial microcompartments that encapsulate the enzymes RuBisCO
and carbonic anhydrase in a proteinaceous shell to enhance the efficiency of photosynthetic …

[HTML][HTML] Rubisco forms a lattice inside alpha-carboxysomes

LA Metskas, D Ortega, LM Oltrogge, C Blikstad… - Nature …, 2022 - nature.com
Despite the importance of microcompartments in prokaryotic biology and bioengineering,
structural heterogeneity has prevented a complete understanding of their architecture …

Incorporation of functional Rubisco activases into engineered carboxysomes to enhance carbon fixation

T Chen, Y Fang, Q Jiang, GF Dykes, Y Lin… - ACS Synthetic …, 2021 - ACS Publications
The carboxysome is a versatile paradigm of prokaryotic organelles and is a proteinaceous
self-assembling microcompartment that plays essential roles in carbon fixation in all …

[HTML][HTML] Protein stoichiometry, structural plasticity and regulation of bacterial microcompartments

LN Liu, M Yang, Y Sun, J Yang - Current Opinion in Microbiology, 2021 - Elsevier
Highlights•Bacterial microcompartments (BMCs) are self-assembling organelles comprising
a protein shell that encapsulates cargo enzymes.•Unraveling the composition and …

Evolutionary relationships among shell proteins of carboxysomes and metabolosomes

MR Melnicki, M Sutter, CA Kerfeld - Current Opinion in Microbiology, 2021 - Elsevier
Highlights•Phylogenomic analysis of shell proteins uncovers supra-functional
relationships.•Alpha-carboxysome shell proteins arose independently from beta …

Kinetic growth of multicomponent microcompartment shells

C Waltmann, NW Kennedy, CE Mills, EW Roth… - ACS …, 2023 - ACS Publications
An important goal of systems and synthetic biology is to produce high value chemical
species in large quantities. Microcompartments, which are protein nanoshells encapsulating …