Treatment options for inflammatory bowel disease (IBD) reflect a continuing shift from
empiricism to strategies based on improved understanding of the pathophysiology of …

In inflammatory bowel diseases (IBD), it is known that besides genetic and environmental
factors (eg diet, drugs, stress), the microbiota play an important role in the pathogenesis …

To investigate the pathogenic mechanism of ulcerative colitis, a dextran sulfate sodium
(DSS)-induced acute colitis model was examined by serum metabolomic analysis. Higher …

Background & aims: Dietary fiber has been proven to be beneficial in maintaining remission
in human ulcerative colitis, an effect related with an increased luminal production of short …

Background & Aims: Intestinal fibrosis and stricture formation are serious complications of
Crohn's disease, often requiring surgical intervention. Unfortunately, the mechanisms …

Aims: The aim of this work was to engineer a gut commensal bacterium, Bacteroides ovatus,
to produce and secrete a biologically active cytokine in a regulated manner as a basis for …

溃疡性结肠炎(ulcerative colitis, UC) 是一种主要局限于大肠黏膜和黏膜下层的慢性非特异性
炎症性疾病, 呈反复发作, 临床表现主要为腹痛, 腹泻, 黏液脓血便. 有资料统计 …

Crohn's disease (CD) is an immune-mediated gastrointestinal inflammatory disease, which
could arise from an interplay between genetic and environmental factors. Klebsiella …

AIM To elucidate the impact of Schistosoma (S.) japonicum infection on inflammatory bowel
disease by studying the effects of exposure to S. japonicum cercariae on dextran sodium …

人类肠道微生态是一个包含大量肠道微生物的复杂生态系统, 近年来研究发现肠道细菌过度繁殖
可导致胃肠道动力失调及内脏神经敏感性改变, 最终导致肠易激综合征的发生 …