Hexamethylbisacetamide (HMBA) induces human immunodeficiency virus type 1 (HIV-1)
gene expression in latently infected T-cell and monocytoid cell lines. We find that HMBA …

Sooty mangabeys, the natural host of simian immunodeficiency virus (SIVsm), generally
avoid progressive depletion of CD4+ T cells and opportunistic infections associated with …

HIV remains incurable because of viral persistence in latent reservoirs that are inaccessible
to antiretroviral therapy. A potential curative strategy is to reactivate viral gene expression in …

See Articles page 572 enhance this effect? 11 Ultimately, more information is needed to
characterise HIV-infected CD4 memory subsets better in different tissue compartments, and …

Cationic liposome-DNA (lipoplexes) or polymer-DNA (polyplexes) complexes have been
used to deliver therapeutic genes, both in vitro and in vivo. However, gene transfer by these …

Upon HIV infection, a subset of latently infected cells carrying transcriptionally inactive
integrated proviral DNA (the HIV-1 reservoir) is rapidly established. These cells are the main …

Predictions made soon after the introduction of human immunodeficiency virus type-1 (HIV-
1) protease inhibitors about potentially eradicating the cellular reservoirs of HIV-1 in infected …

Objective: To investigate if breast milk interleukin [IL]-7 concentrations are associated with
postnatal HIV transmission. Design: A case-control study nested within a cohort of women …

Macrophages and CD4+ T cells are natural target cells for HIV-1, and both cell types
contribute to the establishment of the viral reservoir that is responsible for continuous …

The therapeutic armamentarium for human immunodeficiency virus type 1 (HIV-1) infection
continues to expand. New targets such as entry and integration have recently been …