[HTML][HTML] Beneficial properties of bromelain

P Hikisz, J Bernasinska-Slomczewska - Nutrients, 2021 - mdpi.com
Bromelain is a major sulfhydryl proteolytic enzyme found in pineapple plants, having
multiple activities in many areas of medicine. Due to its low toxicity, high efficiency, high …

[HTML][HTML] Plant-derived natural products in cancer research: extraction, mechanism of action, and drug formulation

WH Talib, I Alsalahat, S Daoud, RF Abutayeh… - Molecules, 2020 - mdpi.com
Cancer is one of the main causes of death globally and considered as a major challenge for
the public health system. The high toxicity and the lack of selectivity of conventional …

[HTML][HTML] Anticancer properties of bromelain: State-of-the-art and recent trends

R Pezzani, M Jimenez-Garcia, X Capo… - Frontiers in …, 2023 - frontiersin.org
Bromelain is a key enzyme found in pineapple (Ananas comosus (L.) Merr.); a proteolytic
substance with multiple beneficial effects for human health such as anti-inflammatory …

Bromelain: A review of its mechanisms, pharmacological effects and potential applications

V Kumar, B Mangla, S Javed, W Ahsan, P Kumar… - Food & Function, 2023 - pubs.rsc.org
The utilization of plant-derived supplements for disease prevention and treatment has long
been recognized because of their remarkable potential. Ananas comosus, commonly known …

[HTML][HTML] Punicalagin, a pomegranate compound, induces apoptosis and autophagy in acute leukemia

P Subkorn, C Norkaew, K Deesrisak, D Tanyong - PeerJ, 2021 - peerj.com
Background Punicalagin is the major phenolic compound found in pomegranate peels. It
has several reported medical benefits, including antioxidant, anti-inflammatory, and …

Proteins and their functionalization for finding therapeutic avenues in cancer: Current status and future prospective

S Mohanty, S Panda, U Devadharshini… - Biochimica et Biophysica …, 2023 - Elsevier
Despite the remarkable advancement in the health care sector, cancer remains the second
most fatal disease globally. The existing conventional cancer treatments primarily include …

[HTML][HTML] Encapsulation of bromelain in combined sodium alginate and amino acid carriers: Experimental design of simplex-centroid mixtures for digestibility evaluation

PC Ricardo, RL Serudo, Ş Ţălu, CV Lamarão… - Molecules, 2022 - mdpi.com
Bromelain has potential as an analgesic, an anti-inflammatory, and in cancer treatments.
Despite its therapeutic effects, this protein undergoes denaturation when administered …

Cytotoxic effect of bromelain on HepG2 hepatocellular carcinoma cell line

SS Murthy, TB Narsaiah - Applied Biochemistry and Biotechnology, 2021 - Springer
Cancer is a complicated long-term disease due to computable key molecular players
involved in aggravating the disease. Among various kinds of cancer, hepatocellular …

A phytopharmacological review on Ananas comosus

B Debnath, WS Singh, K Manna - Advances in Traditional Medicine, 2023 - Springer
Medicinal plants are an immense source of biologically active substances. Ananas comosus
is a fruit base medicinal plant belonging to the family Bromeliaceae. In English it is …

[HTML][HTML] High Retention and Purification of Bromelain Enzyme (Ananas comosus L. Merrill) from Pineapple Juice Using Plain and Hollow Polymeric Membranes …

FMC Gamarra, JCC Santana, SAV Llanos, JAH Pérez… - Polymers, 2022 - mdpi.com
The demand for bromelian and pineapple fruit has been increasing substantially in the world
because of their benefits for the human health and use in diverse areas. In this context, this …