Physical exercise may improve cognitive function by modulating molecular and cellular
mechanisms within the brain. We propose that the facilitation of long-term synaptic …

Research demonstrates that the neural mechanisms underlying synaptic plasticity and
learning and memory involve mobilization of AMPA‐type neurotransmitter receptors at …

Plasmalogens (Pls), a kind of glycerophospholipids, have shown potent biological effects
but their role in hippocampus-dependent memory remained mostly elusive. Here, we first …

Cumulative animal and human studies have consistently demonstrated that two major
cortical regions in the brain, namely the anterior cingulate cortex (ACC) and insular cortex …

Alzheimer's disease (AD) is the most common degenerative disease and is indicative of
dementia. The cerebral accumulation of amyloid β (Aβ), a crucial factor in AD, initiates …

Oxytocin (OXT) is a neuropeptide hormone that plays a critical role in nociception. Long‐
term potentiation (LTP) is a major form of synaptic plasticity in the central nervous system …

Synaptic plasticity such as Long-term potentiation (LTP) is a key mechanism for learning in
central synapses including the cortex. There are two least two major forms of LTPs …

Long-term potentiation (LTP) is a key cellular mechanism for learning and memory, and
recent studies in the hippocampus found that LTP was impaired in aged animals. Previous …

Brain-derived neurotrophic factor (BDNF) signals through tropomyosin receptor kinase B
(TrkB), to exert various types of plasticity. The exact involvement of BDNF and TrkB in …

Fear memory recruits various brain regions with long-lasting brain-wide subcellular events.
The medial prefrontal cortex processes the emotional and cognitive functions required for …