Functional and biomimetic materials for engineering of the three-dimensional cell microenvironment
The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …
Ice templating soft matter: fundamental principles and fabrication approaches to tailor pore structure and morphology and their biomedical applications
Porous scaffolds are widely used in biomedical applications where pore size and
morphology influence a range of biological processes, including mass transfer of solutes …
morphology influence a range of biological processes, including mass transfer of solutes …
[HTML][HTML] Modern trends for peripheral nerve repair and regeneration: beyond the hollow nerve guidance conduit
Peripheral nerve repair and regeneration remains among the greatest challenges in tissue
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …
engineering and regenerative medicine. Even though peripheral nerve injuries (PNIs) are …
In vivo engineered extracellular matrix scaffolds with instructive niches for oriented tissue regeneration
M Zhu, W Li, X Dong, X Yuan, AC Midgley… - Nature …, 2019 - nature.com
Implanted scaffolds with inductive niches can facilitate the recruitment and differentiation of
host cells, thereby enhancing endogenous tissue regeneration. Extracellular matrix (ECM) …
host cells, thereby enhancing endogenous tissue regeneration. Extracellular matrix (ECM) …
[HTML][HTML] Anisotropic scaffolds for peripheral nerve and spinal cord regeneration
The treatment of long-gap (> 10 mm) peripheral nerve injury (PNI) and spinal cord injury
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
(SCI) remains a continuous challenge due to limited native tissue regeneration capabilities …
Aligned microfiber-induced macrophage polarization to guide schwann-cell-enabled peripheral nerve regeneration
X Dong, S Liu, Y Yang, S Gao, W Li, J Cao, Y Wan… - Biomaterials, 2021 - Elsevier
Mechanistic understanding of the topological cues delivered by biomaterials in promotion of
oriented tissue regeneration (eg., peripheral nerve regrowth) remains largely elusive. Here …
oriented tissue regeneration (eg., peripheral nerve regrowth) remains largely elusive. Here …
Aligned conductive core-shell biomimetic scaffolds based on nanofiber yarns/hydrogel for enhanced 3D neurite outgrowth alignment and elongation
Aligned topographical cue has been demonstrated as a critical role in neuronal guidance,
and it is highly beneficial to develop a scaffold with aligned structure for peripheral nerve …
and it is highly beneficial to develop a scaffold with aligned structure for peripheral nerve …
A review on fabricating tissue scaffolds using vat photopolymerization
Abstract Vat Photopolymerization (stereolithography, SLA), an Additive Manufacturing (AM)
or 3D printing technology, holds particular promise for the fabrication of tissue scaffolds for …
or 3D printing technology, holds particular promise for the fabrication of tissue scaffolds for …
From nano to micro: topographical scale and its impact on cell adhesion, morphology and contact guidance
Topography, among other physical factors such as substrate stiffness and extracellular
forces, is known to have a great influence on cell behaviours. Optimization of topographical …
forces, is known to have a great influence on cell behaviours. Optimization of topographical …
Engineering microscale topographies to control the cell–substrate interface
Cells in their in vivo microenvironment constantly encounter and respond to a multitude of
signals. While the role of biochemical signals has long been appreciated, the importance of …
signals. While the role of biochemical signals has long been appreciated, the importance of …