Synthesis, characterization, molecular docking and in vitro anti-cancer activity studies of new and highly selective 1, 2, 3-triazole substituted 4-hydroxybenzohyrdazide …
In this study, 16 new hybrid compounds 6 (ah) and 7 (ah) were synthesized starting from
methylparaben. These new compounds consist of eight 1, 2, 3-triazole-arylidenehydrazide …
methylparaben. These new compounds consist of eight 1, 2, 3-triazole-arylidenehydrazide …
Novel chalcone derivatives of ursolic acid as acetylcholinesterase inhibitors: Synthesis, characterization, biological activity, ADME prediction, molecular docking and …
Acetylcholinesterase (AChE) is a critical target in the prevention of Alzheimer's Disease (AD)
progression. With the goal of developing potential acetylcholinesterase inhibitors, a new …
progression. With the goal of developing potential acetylcholinesterase inhibitors, a new …
Cytotoxic meroterpenoids from brown alga Stypopodium schimperi (Kützing) Verlaque & Boudouresque with comprehensive molecular docking & dynamics and …
In this study, five known meroterpenoids sargaol (1), flabellinone (2), stypodiol (3),
atomarianone A (4), atomarianone B (5), and a known steroid fucosterol (6) were isolated …
atomarianone A (4), atomarianone B (5), and a known steroid fucosterol (6) were isolated …
Synthesis, Characterization, Molecular Docking and in vitro Biological Studies of Thiazolidin‐4‐one Derivatives as Anti‐Breast‐Cancer Agents
In this study, 16 new compounds were synthesized starting from methylparaben. These new
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …
Synthesis of nitrogen-containing oleanolic acid derivatives as carbonic anhydrase and acetylcholinesterase inhibitors
In this study, a total of 13 compounds (5–17) were synthesized starting from oleanolic acid
(OA), a natural triterpenoid. Five new compounds (10, 11, 12, 15 and 17), are the main …
(OA), a natural triterpenoid. Five new compounds (10, 11, 12, 15 and 17), are the main …
3‐Amino‐thiophene‐2‐carbohydrazide derivatives as anti Colon cancer Agents: synthesis, characterization, in‐Silico and in‐Vitro Biological activity studies
In this study, starting from 3‐amino‐thiophene‐2‐carboxylic acid methyl ester, eighteen new
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
arylidenehydrazide derivatives (4–21) were synthesized. To determine cytotoxic activity of …
Novel quinazoline–chromene hybrids as anticancer agents: Synthesis, biological activity, molecular docking, dynamics and ADME studies
In this study, new quinazoline–chromene hybrid compounds were synthesized. The
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …
cytotoxic effects on cell viability of the hybrid compounds were tested against A549 human …
Synthesis and anticancer activity of novel derivatives of α, β‐unsaturated ketones based on oleanolic acid: in vitro and in silico studies against prostate cancer cells
Herein, new derivatives of α, β-unsaturated ketones based on oleanolic acid (4 ai) were
designed, synthesized, characterized, and tested against human prostate cancer (PC3) …
designed, synthesized, characterized, and tested against human prostate cancer (PC3) …
Novel complex compounds of nickel with 3-(1-phenyl-2, 3-dimethyl-pyrazolone-5) azopentadione-2, 4: synthesis, NBO analysis, reactivity descriptors and in silico and …
S Tahirli, F Aliyeva, H Şenol… - Journal of …, 2024 - Taylor & Francis
A synthesized azo compound based on 4-amino antipyrine and its complexes with Ni (II) in
solution and solid phase is reported. The structures of these compounds have been testified …
solution and solid phase is reported. The structures of these compounds have been testified …
New tetrahydro-isoquinoline derivatives as cholinesterase and α-glycosidase inhibitors: Synthesis, characterization, molecular docking & dynamics, ADME prediction …
In the presented work, it was reported about the synthesis procedure of new isoquinoline
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …
derivatives starting from chalcones and acetoacetanilide, a multi-step synthesis pathway …