The reliability of organic molecular crystal structure prediction has improved tremendously in
recent years. Crystal structure predictions for small, mostly rigid molecules are quickly …

Twenty years ago, I wrote a Chem. Commun. feature article entitled “Crystal Engineering:
where from? Where to?”: an update is in order. In this Highlight I argue that molecular crystal …

In this study, the existing set of carbamazepine (CBZ) cocrystals was extended through the
successful combination of the drug with the positional isomers of acetamidobenzoic acid …

Pharmaceutical co-crystals represent a growing class of crystal forms in the context of
pharmaceutical science. They are attractive to pharmaceutical scientists because they …

Polymorphism is a common phenomenon among single-and multicomponent molecular
crystals that has a significant impact on the contemporary drug development process. A new …

The development of multicomponent crystal forms, such as cocrystals, represents a means
to enhance the dissolution and absorption properties of poorly water-soluble drug …

Pharmaceutical cocrystals are crystalline materials composed of at least two molecules, ie,
an active pharmaceutical ingredient (API) and a coformer, assembled by noncovalent forces …

The application of computational screening methodologies based on H-bond propensity
scores, molecular complementarity, molecular electrostatic potentials, and crystal structure …

Hydrogen-bonded supramolecular assemblies of citric acid, CA, with some heterocyclic
compounds (N-donor and N-oxide)─ acridine (acr), phenazine (phenz), 1, 10 …

The antiepilepsy drug carbamazepine is one of the most studied pharmaceuticals in the
world. The rich story of its solid forms, cocrystals, and formulation is a microcosm of the …