Posttraumatic stress disorder can be viewed as a disorder of fear dysregulation. An
abundance of research suggests that the prefrontal cortex is central to fear processing—that …

Mnemonic functions, supporting rodent behavior in complex tasks, include both long-term
and (short-term) working memory components. While working memory is thought to rely on …

Dysregulation of habit formation has been recently proposed as pivotal to eating disorders.
Here, we report that a subset of patients suffering from restrictive anorexia nervosa have …

Adaptive reward-related decision making requires accurate prospective consideration of the
specific outcome of each option and its current desirability. Often this information must be …

Day-to-day choices often involve social information and can be influenced by prior social
experience. When making a decision in a social context, a subject might need to: 1) …

Pain is a multifaceted process that encompasses unpleasant sensory and emotional
experiences. The essence of the pain process is aversion, or perceived negative emotion …

Habits are an important mechanism by which organisms can automate the control of
behavior to alleviate cognitive demand. However, transitions to habitual control are risky …

Social experiences influence decision making, including decision making lacking explicit
social content, yet mechanistic factors are unclear. We developed a new procedure, social …

Successfully navigating dynamic environments requires organisms to learn the
consequences of their actions. The prelimbic prefrontal cortex (PL) formulates action …

Social experiences carry tremendous weight in our decision-making, even when social
partners are not present. To determine mechanisms, we trained female mice to respond for …