DNA methylation is a fundamental mechanism of epigenetic control in cells and its
dysregulation is strongly implicated in cancer development. Cancers possess an extensively …

DNA methylation is a pivotal epigenetic modification that affects gene expression. Tumor
immune microenvironment (TIME) comprises diverse immune cells and stromal …

In many hematologic malignancies, the adoptive transfer of chimeric antigen receptor (CAR)
T cells has demonstrated notable success; nevertheless, further improvements are …

The development of age-associated diseases is related to the accumulation of senescent
cells in the body. These are old non-functional cells with impaired metabolism, which are …

DNA methylation is a key epigenetic regulatory mechanism that plays a critical role in a
variety of cellular processes, including the regulation of cell fate during development …

Tertiary lymphoid structures (TLS) are ectopic lymphoid aggregates found in sites of chronic
inflammation such as tumors and autoimmune diseases. The discovery that TLS formation at …

Wood frogs are freeze-tolerant vertebrates that can endure weeks to months frozen during
the winter without breathing and with as much as 65% of total body water frozen as …

Triple-negative breast cancer (TNBC) is one of the major clinical problems to be solved
urgently, because of its high malignancy, poor targeted therapy effect and easy occurrence …

Exosomes are increasingly recognized as important mediators of intercellular
communication in cancer biology. Exosomes can be derived from cancer cells as well as …

Background Nasopharyngeal carcinoma (NPC) is a common malignancy occurring in the
head and neck. Identification of immune‐related methylated biomarkers might be helpful for …