Vascular cognitive impairment (VCI) is predominately caused by vascular risk factors and
cerebrovascular disease. VCI includes a broad spectrum of cognitive disorders, from mild …

The global prevalence of dementia has been estimated to be as high as 24 million, and is
predicted to double every 20 years until at least 2040. As the population worldwide …

With increasing knowledge of clinical in vivo biomarkers and the pathological intricacies of
Alzheimer's disease (AD), nosology is evolving. Harmonized consensus criteria that …

Executive functioning deficits due to brain disease affecting frontal lobe functions cause
significant real-life disability, yet solid evidence in support of executive functioning …

Most strokes are covert and observed incidentally on brain scans, but their presence
increases risk of overt stroke and dementia. Amyloid angiopathy, associated with Alzheimer …

Alzheimer's disease is a heterogeneous disorder. Understanding the biological basis for this
heterogeneity is key for developing personalized medicine. We identified atrophy subtypes …

The thalamus is a crucial node for brain physiology and part of functional and structural
pathways relevant for schizophrenia. Relatively few imaging studies on schizophrenia have …

Background: Neuropathologic studies suggest an association between cerebral amyloid
angiopathy (CAA) and small ischemic infarctions as well as hemorrhages. We examined the …

Objective We hypothesized that vascular amyloid contributes to chronic brain ischemia,
therefore amyloid burden measured by Pittsburgh compound B retention on positron …

Vascular dementia/vascular cognitive impairment (VaD/VCI) is not a single entity, but a large
group of conditions characterized by various clinical and morphological findings and …