Background Our aim was to explore the indications for and outcome of biological prostheses
to repair high risk abdominal wall defects in children. Methods A retrospective chart review …

Aims: Closure of congenital body wall defects in children can be a challenging task for the
pediatric Surgeon. Biological prosthesis has been increasingly used for high-risk wound …

The field of tissue engineering/regenerative medicine is based upon the following
fundamental strategies to promote functional tissue replacement: cell‐based therapies …

Purpose Due to the large abdominal defect from the omphalocele and extreme pubic
diastasis in cloacal exstrophy (CE), bioprosthetic material may be used to bridge this gap …

Skin provides a critical protective barrier for humans, maintaining fluid homeostasis and
preventing microorganism invasion. Other important functions include temperature control …

Giant omphalocele (GO) represents a challenge for paediatric surgeons. Management of GO
has been discussed extensively over the past 50 years but still represents a topic of debate …

Gastroschisis defects are managed with a variety of strategies including primary closure,
staged silo reduction with delayed repair, and sutureless closure techniques. In cases of …

Disrupted organogenesis leads to permanent malformations that may require surgical
correction. Affected new-borns without spare tissue for the primary closure are dependent of …

Francis Crick proposed the central dogma of molecular biology more than a half century ago
focusing on the role of RNA as a messenger which delivers genetic information from DNA to …