Proteins control many vital functions in living cells, such as cell growth and cell division.
Reliable coordination of these functions requires the spatial and temporal organization of …

Remodeling of the intracellular cytoskeleton plays a key role in accelerating tumor growth
and metastasis. Targeting different cytoskeletal elements is important for existing and future …

Abstract The F-BAR protein Cdc15 is essential for cytokinesis in Schizosaccharomyces
pombe and plays a key role in attaching the cytokinetic ring (CR) to the plasma membrane …

The survival of eukaryotic organisms during environmental changes is largely dependent on
the adaptive responses elicited by signal transduction cascades, including those regulated …

Cytokinesis is the final stage of cell division cycle when cellular constituents are separated
to produce two daughter cells. This process is driven by the formation and constriction of a …

Many eukaryotes assemble an actin-and myosin-based cytokinetic ring (CR) on the plasma
membrane (PM) for cell division, but how it is anchored there remains unclear. In …

Cytokinesis, the separation of daughter cells at the end of mitosis, relies in animal cells on a
contractile actomyosin ring (CAR) composed of actin and class II myosins, whose activity is …

The GTPase Cdc42 regulates polarized growth in most eukaryotes. In the bipolar yeast
Schizosaccharomyces pombe, Cdc42 activation cycles periodically at sites of polarized …

Cytokinesis, the conclusive act of cell division, allows cytoplasmic organelles and
chromosomes to be faithfully partitioned between two daughter cells. In animal organisms …

Background. Anillin (ANLN), a ubiquitously expressed actin‐binding protein, plays a critical
tumor‐promoting role in cell growth, migration, and cytokinesis. Numerous studies have …