The theory proposed is that a critical level of specific serum IgG is sufficient to confer
protection against infectious diseases by inactivating the inoculum of the pathogen. This …

Childhood immunization is one of the major public health measures of the 20th century and
is now receiving special attention from the Clinton administration. At the same time, some …

Study objective. To develop guidelines for the care of infants and children from birth to 36
months of age with fever without source. Participants and setting. An expert panel of senior …

The susceptibilities of Streptococcus pneumoniae (1,476 strains) and untypeable
Haemophilus influenzae (1,676 strains) to various oral β-lactam, macrolide-azalide, and …

A total of 1,537 clinical isolates of Haemophilus influenzae were recovered in 30 US medical
center laboratories between 1 November 1994 and 30 April 1995 and were characterized in …

Treatment of pneumococcal meningitis has become problematic because of the emergence
of penicillin-and cephalosporin-resistant strains and because of the concern that …

Background. Introduction of Haemophilus influenzae type b (Hib) vaccines has dramatically
altered the epidemiology of bacterial meningitis in children. The goal of this study was to …

Objective: The incidence of invasive Haemophilus disease has unexpectedly decreased in
unvaccinated children since the introduction of conjugate vaccine in the United States. The …

Glycoconjugate vaccines have been proven safe and effective against various diseases in
children. Although these vaccines have a history of effectiveness, there are still many …

Rates of invasive Haemophilus influenzae type b (Hib) disease in children decreased very
rapidly after licensure of Hib conjugate vaccines. A role for a vaccine-related reduction in …