Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research

L Perez de Souza, S Alseekh, F Scossa, AR Fernie - Nature Methods, 2021 - nature.com
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …

[HTML][HTML] Recurrent topics in mass spectrometry-based metabolomics and lipidomics—standardization, coverage, and throughput

E Rampler, YE Abiead, H Schoeny, M Rusz… - Analytical …, 2020 - ACS Publications
We have come a long way in the last years of developing analytical strategies in
metabolomics. We have seen huge progress in tackling multiplatform measurement, data …

Challenges and emergent solutions for LC‐MS/MS based untargeted metabolomics in diseases

L Cui, H Lu, YH Lee - Mass spectrometry reviews, 2018 - Wiley Online Library
In the past decade, advances in liquid chromatography‐mass spectrometry (LC‐MS) have
revolutionized untargeted metabolomics analyses. By mining metabolomes more deeply …

Adding a new separation dimension to MS and LC–MS: what is the utility of ion mobility spectrometry?

V d'Atri, T Causon, O Hernandez‐Alba… - Journal of separation …, 2018 - Wiley Online Library
Ion mobility spectrometry is an analytical technique known for more than 100 years, which
entails separating ions in the gas phase based on their size, shape, and charge. While ion …

Ion mobility collision cross section compendium

JC May, CB Morris, JA McLean - Analytical chemistry, 2017 - ACS Publications
In this Review, we focus on an important aspect of ion mobility (IM) research, namely, the
reporting of quantitative ion mobility measurements in the form of the gas-phase collision …

[HTML][HTML] The genus Capsicum: a phytochemical review of bioactive secondary metabolites

AS Antonio, LSM Wiedemann, VFV Junior - RSC advances, 2018 - pubs.rsc.org
The Capsicum genus is one of the most popular plants consumed and cultivated worldwide,
containing approximately 50 000 varieties of pepper. Due to its wide biodiversity, the …

Untargeted metabolomics by liquid chromatography‐mass spectrometry for food authentication: A review

P Zhong, X Wei, X Li, X Wei, S Wu… - … Reviews in Food …, 2022 - Wiley Online Library
Food fraud is currently a growing global concern with far‐reaching consequences. Food
authenticity attributes, including biological identity, geographical origin, agricultural …

The potential of ion mobility–mass spectrometry for non-targeted metabolomics

T Mairinger, TJ Causon, S Hann - Current Opinion in Chemical Biology, 2018 - Elsevier
Highlights•IM–MS coupled to separation techniques is attractive for non-targeted
metabolomics.•CCS values are a complementary molecular descriptor for identification …

Deep metabolome annotation in natural products research: towards a virtuous cycle in metabolite identification

PM Allard, G Genta-Jouve, JL Wolfender - Current Opinion in Chemical …, 2017 - Elsevier
Highlights•LC-HRMS provides detailed, high-quality data on natural extracts
metabolomes.•Size of spectral libraries in NPs research is limited but may be increased in …

Ion mobility spectrometry and the omics: Distinguishing isomers, molecular classes and contaminant ions in complex samples

KE Burnum-Johnson, X Zheng, JN Dodds, J Ash… - TrAC Trends in …, 2019 - Elsevier
Ion mobility spectrometry (IMS) is a widely used analytical technique providing rapid gas
phase separations. IMS alone is useful, but its coupling with mass spectrometry (IMS-MS) …