The accumulation of senescent cells within tissues is a hallmark of the aging process.
Senescent cells are also commonly present in many age-related diseases and in the cancer …

Cardiovascular disease (CVD) is a leading cause of morbidity and mortality worldwide, and
senescent cells have emerged as key contributors to its pathogenesis. Senescent cells …

Exposure to crystalline silica (CS) particles in worksites and dwellings can lead to silicosis
due to excessive fibroblast activation. Considering their immuno-regulatory activities, the …

Cellular senescence represents an irreversible state of cell-cycle arrest during which cells
secrete senescence-associated secretory phenotypes, including inflammatory factors and …

Cellular senescence refers to the permanent and irreversible cessation of the cell cycle.
Recently, it has gained significant interest as a promising target for preventing …

Fibrosis is a reparative and progressive process characterized by abnormal extracellular
matrix deposition, contributing to organ dysfunction in chronic diseases. The tumor …

Cellular senescence is a key hallmark of aging. It has now emerged as a key mediator in
normal tissue turnover and is associated with a variety of age-related diseases, including …

Posterior capsule opacification (PCO) is a common complication after cataract surgery.
Residual lens epithelial cells (LECs) on the anterior lens capsule, after cataract surgery …

The accumulation of pro-inflammatory senescent cells within tissues is a common hallmark
of the aging process and many age-related diseases. This modification has been called the …

In contrast to neonates and lower organisms, the adult mammalian heart lacks any capacity
to regenerate following injury. The vast majority of our understanding of cardiac …