Background Surgical abortion by vacuum aspiration or dilatation and curettage has been the
method of choice for early pregnancy termination since the 1960s. Medical abortion became …

Background Medical abortion became an alternative method of pregnancy termination
following the development of prostaglandins and antiprogesterone in the 1970s and 1980s …

Since the original description of the structure of the antiprogestin, mifepristone, was
published, numerous related compounds have been synthesized which may function as …

BACKGROUND: Vaginal misoprostol has been shown to be an effective single agent for
medical abortion. This randomized, double-blinded, placebo-controlled trial compared a …

The pharmacokinetics of mifepristone is characterized by rapid absorption, a long half-life of
25–30 h, and high micromolar serum concentrations following ingestion of doses of≥ 100 …

Objectives To evaluate pain and other early adverse events associated with different
regimens of medical abortion up to nine weeks of amenorrhoea. Methods The literature was …

Emergency contraception is used to prevent pregnancy after unprotected sex but before
pregnancy begins. Currently, women can use emergency contraception by taking higher …

Aim The aim of the present study was to investigate the safety and efficacy of low‐dose
mifepristone combined with self‐administered misoprostol for termination of early …

Objective To compare the efficacy of 100 mg and 200 mg of mifepristone and 24‐and 48‐
hour intervals to administration of 800μg vaginal misoprostol for termination of early …

Objective: The purpose of this study was to evaluate the efficacy, side-effect profile, and
follow-up rates in women who obtain a medical abortion in a nonresearch setting. Study …