Sickle cell disease (SCD), one of the most common monogenetic diseases in the world, is
associated with multisystemic complications that begin in childhood. Most of the babies …

Despite recent developmental screening guidelines, rates of neurodevelopmental disorders
(NDDs) remain lower than expected in children with sickle cell disease (SCD). A …

This study aimed to synthesize the evidence on the effects of disease‐modifying agents for
managing sickle cell disease (SCD) in children and adolescents by means of a systematic …

Combination dose-escalated hydroxyurea and transfusion: an approach to conserve blood
during the COVID-19 pandemic | Blood | American Society of Hematology Skip to Main Content …

Despite its high prevalence in children with sickle cell anemia (SCA), the pathophysiology of
silent cerebral infarcts (SCI) remains elusive. The main objective of this study was to explore …

Background: Children with sickle cell disease (SCD), a genetic blood disorder, are at
increased risk of developmental delays but are not routinely referred to Early Intervention …

Importance Adults with sickle cell disease (SCD) disproportionally experience early
cognitive decline; however, guidance on the optimal screening strategy for cognitive …

Background: Hemorrhagic stroke in young patients with sickle cell anemia remains poorly
characterized. Methods: The Post-STOP (Stroke Prevention Trial in Sickle Cell Anemia) …

Background. Sickle cell disease (SCD) is a life‐threatening genetic disorder due to the
formation of sickle hemoglobin molecule (HbS) that polymerizes in hypoxic conditions …

Pregnant individuals with sickle cell disease have an increased risk of maternal and
perinatal morbidity and mortality. However, prepregnancy counseling and multidisciplinary …